4 documents found, page 1 of 1
Occurrence of tet(O/M/O) mosaic gene in tetracycline-resistant Campylobacter
Hormeño, Lorena; Campos, Maria J.; Vadillo, Santiago; Quesada, AlbertoCampylobacter is one of the most important microorganisms responsible for foodborne diseases in the EU. In this study, we investigated resistance to tetracycline in 139 Campylobacter jejuni and Campylobacter coli samples isolated from human clinical cases. From these, 110 were resistant to tetracycline, with MIC (minimal inhibitory concentration) varying in a range of 1 to >512 ug/mL, and 109 (78.4%) carried te...
ant(6)-I Genes encoding aminoglycoside O-nucleotidyltransferases are widely spr...
Hormeño, Lorena; Ugarte-Ruiz, María; Palomo, Gonzalo; Borge, Carmen; Florez-Cuadrado, Diego; Vadillo, Santiago; Píriz, Segundo; Domínguez, Lucas
Identification of the main quinolone resistance determinant in Campylobacter je...
Hormeño, Lorena; Palomo, Gonzalo; Ugarte-Ruiz, María; Porrero, M. Concepción; Borge, Carmen; Vadillo, Santiago; Píriz, Segundo; Domínguez, LucasAmong zoonotic diseases, campylobacteriosis stands out as the major bacterial infection producing human gastroenteritis. Antimicrobial therapy, only recommended in critical cases, is challenged by resistance mechanisms that should be unambiguously detected for achievement of effective treatments. Quinolone (ciprofloxacin) resistance of Campylobacter jejuni and Campylobacter coli, the2main Campylobacter detected...
Detection of QnrB54 and Its Novel Genetic Context in Citrobacter freundii Isola...
Campos, Maria Jorge; Palomo, Gonzalo; Hormeño, Lorena; Rodrigues, Américo; Sánchez-Benito, Rosario; Píriz, Segundo; Quesada, AlbertoLETTER Quinolone resistance in Enterobacteriaceae is mediated by mutations in the quinolone resistance-determining regions (QRDR) of topoisomerase genes and/or by plasmid-mediated quinolone resistance determinants (PMQR) such as the qnr genes encoding pentapeptide repeat proteins (1). The qnrB family is represented by 80 different alleles (http://www.lahey.org/qnrStudies/); most of them originated from Citrobac...