14 documents found, page 1 of 2
Efeito agudo da prática do ténis no tempo de reação simples de jovens em idades...
Horta, BrunoO presente documento, denominado de Relatório Final de Estágio, surge como o culminar do processo de formação e tem como principal finalidade a reflexão sobre todos os aspetos e atividades desenvolvidas ao longo da unidade curricular de Prática de Ensino Supervisionada, integrada no 2º ciclo em Ensino de Educação Física nos Ensinos Básico e Secundário, do Instituto Superior de Estudos Interculturais e Transdisc...
In vivo study of the effect of sugarcane bagasse lignin supplementation on broi...
Carvalho, Nelson Mota de; Souza, Carla Giselly de; Costa, Célia Maria; Castro, Cláudia; Fangueiro, Joana F.; Horta, Bruno; Outor-Monteiro, DivanildoSince the global restrictions on antibiotics in poultry systems, there has been a growing demand for natural and sustainable feed additives for disease prevention and poultry nutrition. This study evaluated the effects of incorporating sugarcane bagasse (SCB) lignin into broiler chicken diets. The performance of the chickens, including body weight, feed intake, and mortality, as well as intestinal histomorphome...
Antitumor effect of chalcone derivatives against human prostate (LNCaP and PC-3...
Horta, Bruno; Freitas-Silva, Joana; Silva, Jani; Dias, Francisca; Teixeira, Ana Luísa; Medeiros, Rui; Cidade, Honorina; Pinto, MadalenaChalcones are synthetic and naturally occurring compounds that have been widely investigated as anticancer agents. In this work, the effect of chalcones 1–18 against the metabolic viability of cervical (HeLa) and prostate (PC-3 and LNCaP) tumor cell lines was tested, to compare the activity against solid and liquid tumor cells. Their effect was also evaluated on the Jurkat cell line. Chalcone 16 showed the high...
Cervical cancer outcome and tumor-associated macrophages: research evidence
Horta, Bruno; Pereira, Tomé; Medeiros, R.; Cerqueira, FátimaInflammation is a key factor in cancer promotion. Tumor-associated macrophages (TAMs), as part of the tumor microenvironment, are often associated with the progression of tumors and a worse prognosis in many cancers, namely on cervical cancer. This work exhaustively summarizes the conclusions of the different studies published concerning TAMs function in cervical cancer, from in vitro studies using cancer cell ...
Valorization of spent sugarcane fermentation broth as a source of phenolic comp...
Oliveira, Carla Maria; Horta, Bruno; Leal, Tânia; Pintado, Manuela; Oliveira, Catarina S. S.A methodology based on a solid phase extraction (SPE) was optimized for the recovery of phenolic compounds from the spent fermentation broth generated from Biofene® (trans-β-farnesene) production. For this purpose, two resins (XAD-2 and HP-20) and three desorption solutions (water, 50/50 ethanol/water, and ethanol) were tested. The most efficient resin revealed to be the HP-20, using ethanol as desorption solut...
Fractionating of synthetic biology waste stream into nutrient rich extract for ...
Horta, Bruno; Cálix, Carla; Burgal, João; Oliveira, CatarinaAmyris is a world-leading manufacturer of sustainable ingredients producing environmentally friendly products. Biofene® (or trans-β-farnesene) is a synthetic biology derived product using yeast fermentation of sugarcane. This production originates spent broth, an aqueous waste stream typically applied to land by fertirrigation. On one hand, spent broth contains recoverable added-value compounds; on the other ha...
Effect of 1-carbaldehyde-3,4-dimethoxyxanthone on prostate and HPV-18 positive ...
Medeiros, R.; Horta, Bruno; Freitas-Silva, Joana; Silva, Jani; Dias, Francisca; Sousa, Emília; Pinto, Madalena; Cerqueira, FátimaXanthone derivatives have shown promising antitumor properties, and 1-carbaldehyde-3,4- dimethoxyxanthone (1) has recently emerged as a potent tumor cell growth inhibitor. In this study, its effect was evaluated (MTT viability assay) against a new panel of cancer cells, namely cervical cancer (HeLa), androgen-sensitive (LNCaP) and androgen-independent (PC-3) prostate cancer, and nonsolid tumor derived cancer (J...
Omega 3 and resveratrol loaded lipid nanosystems for potential use as topical f...
Caldas, Ana Rita; Catita, José; Machado, Raúl; Ribeiro, Artur; Cerqueira, Fátima; Horta, Bruno; Medeiros, R.; Lúcio, Marlene; Lopes, Carla MartinsResveratrol (RSV) and omega 3 (ω3), because of their biological favorable properties, have become subjects of interest for researchers in dermocosmetic and pharmaceutical industries; however, these bioactives present technological limitations that hinder their effective delivery to the target skin layer. To overcome the stability and skin permeation limitations of free bioactives, this work proposes a combined ...
Omega-3- and resveratrol-loaded lipid nanosystems for potential use as topical ...
Caldas, Ana R.; Catita, José; Machado, Raul; Ribeiro, Artur; Cerqueira, Fátima; Horta, Bruno; Medeiros, Rui; Lúcio, Marlene; Lopes, Carla M.Resveratrol (RSV) and omega 3 (!3), because of their biological favorable properties, have become subjects of interest for researchers in dermocosmetic and pharmaceutical industries; however, these bioactives present technological limitations that hinder their effective delivery to the target skin layer. To overcome the stability and skin permeation limitations of free bioactives, this work proposes a combined ...
Effect of 1-carbaldehyde-3,4-dimethoxyxanthone on prostate and HPV-18 positive ...
Medeiros, Rui; Horta, Bruno; Freitas-Silva, Joana; Silva, Jani; Dias, Francisca; Sousa, Emília; Pinto, Madalena; Cerqueira, FátimaXanthone derivatives have shown promising antitumor properties, and 1-carbaldehyde-3,4-dimethoxyxanthone (1) has recently emerged as a potent tumor cell growth inhibitor. In this study, its effect was evaluated (MTT viability assay) against a new panel of cancer cells, namely cervical cancer (HeLa), androgen-sensitive (LNCaP) and androgen-independent (PC-3) prostate cancer, and nonsolid tumor derived cancer (Ju...