9 documents found, page 1 of 1
Stromal vascular fraction obtained from subcutaneous adipose tissue: ex-obese a...
Frias, Frias; Matos, Beatriz; Jarnalo, Mariana; Freitas-Ribeiro, Sara; Reis, R. L.; Pirraco, Rogério P.; Horta, RicardoIntroduction. Human adipose tissue contains a heterogeneous and synergistic mixture of cells called stromal vascular fraction (SVF) with highly proliferative and angiogenic properties, conferring promising applicability in the field of regenerative medicine. This study aims to investigate if age, body mass index (BMI), history of obesity and massive weight loss, and harvest site are related to SVF cell marker e...
Pre-selection of fibroblasts subsets prompt prevascularization of tissue engine...
Moreira, Helena R.; Cerqueira, Mariana T.; Silva, Lucília Pereira; Pires, Joana; Jarnalo, Mariana; Horta, Ricardo; Reis, R. L.; Marques, A. P.The papillary and reticular dermis harbors phenotypically distinct fibroblasts, whose functions such as maintenance of skin's microvasculature are also distinct. Thus, we hypothesized that pre-selection of the subpopulations of fibroblasts would benefit the generation of skin tissue engineered (TE) constructs, promoting their prevascularization in vitro. We first isolated papillary and reticular fibroblasts usi...
Spongy-like hydrogels prevascularization with the adipose tissue vascular fract...
Moreira, Helena R.; Rodrigues, Daniel Barreira; Ribeiro, Sara Freitas; Silva, Lucília Pereira; Morais, Alain da S.; Jarnalo, Mariana; Horta, RicardoIn vitro prevascularization is one of the most explored approaches to foster engineered tissue vascularization. We previously demonstrated a benefit in tissue neovascularization by using integrin-specific biomaterials prevascularized by stromal vascular fraction (SVF) cells, which triggered vasculogenesis in the absence of extrinsic growth factors. SVF cells are also associated to biological processes important...
Integrin-specific hydrogels for growth factor-free vasculogenesis
Moreira, Helena R.; Rodrigues, Daniel Barreira; Ribeiro, Sara Freitas; Silva, Lucília Pereira; Morais, Alain da S.; Jarnalo, Mariana; Horta, RicardoIntegrin-binding biomaterials have been extensively evaluated for their capacity to enable de novo formation of capillary-like structures/vessels, ultimately supporting neovascularization in vivo. Yet, the role of integrins as vascular initiators in engineered materials is still not well understood. Here, we show that αvβ3 integrin-specific 3D matrices were able to retain PECAM1+ cells from the stromal vascu...
Growth factor-free vascularization of marine-origin collagen sponges using cryo...
Freitas-Ribeiro, Sara; Diogo, Gabriela S.; Oliveira, Catarina; Martins, Albino; Silva, Tiago H.; Jarnalo, Mariana; Horta, Ricardo; Reis, R. L.The successful integration of transplanted three-dimensional tissue engineering (TE) constructs depends greatly on their rapid vascularization. Therefore, it is essential to address this vascularization issue in the initial design of constructs for perfused tissues. Two of the most important variables in this regard are scaffold composition and cell sourcing. Collagens with marine origins overcome some issues a...
Epidemiological Profile in Portugal of Breast Implant-Associated Anaplastic Lar...
Cunha, Adriana; Horta, Ricardo; Barreiro, DiogoIntroduction: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell neoplasm that is predominantly associated with the use of textured implants. Recently, several countries have tried to clarify their epidemiological profile of BIA-ALCL. This study aims to estimate the number of cases of BIA-ALCL in Portugal and to describe the pattern of use of breast implants at a national level...
The IMBPC HVAC system: a complete MBPC solution for existing HVAC systems
Ruano, Antonio; Pesteh, Shabnam; Silva, Sergio; Duarte, Helder; Mestre, Gonçalo; Ferreira, Pedro M.; Khosravani, Hamid Reza; Horta, RicardoThis paper introduces the Intelligent MBPC (IMBPC) HVAC system, a complete solution to enable Model Based Predictive Control (MBPC) of existing HVAC installations in a building. The IMPBC HVAC minimizes the economic cost needed to maintain controlled rooms in thermal comfort during the periods of occupation. The hardware and software components of the IMBPC system are described, with a focus on the MBPC algorit...
Secondary Rhinoplasty Using the Technique of Turkish Delight: a Case Report and...
Correia-Sá, Inês; Amarante, José; Horta, Ricardo; Neto, Tiago; Silva, Álvaro; Marques, MarisaRhinoplasty is a demanding task, especially when augmentation of the nasal contour is required. Autologous cartilage grafts are challenging. Contour and alignment of the graft are difficult goals. It is presented a case of a successfully nasal dorsum augmentation in a secondary rhinoplasty with the Turkish Delight technique and a brief review of literature. A 33-years-old female, with history of complete unilat...
An Intelligent Weather Station
Mestre, Goncalo; Ruano, Antonio; Duarte, Helder; Silva, Sergio; Khosravani, Hamid Reza; Pesteh, Shabnam; Ferreira, Pedro M.; Horta, RicardoAccurate measurements of global solar radiation, atmospheric temperature and relative humidity, as well as the availability of the predictions of their evolution over time, are important for different areas of applications, such as agriculture, renewable energy and energy management, or thermal comfort in buildings. For this reason, an intelligent, light-weight, self-powered and portable sensor was developed, u...