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Anesthesia for muscle biopsy to test susceptibility to malignant hyperthermia

Silva,Helga Cristina Almeida da; Onari,Elton Shinji; Castro,Isac de; Perez,Marcelo Vaz; Hortensi,Alexandre; Amaral,José Luiz Gomes do

Abstract Introduction Malignant hyperthermia is an autosomal dominant pharmacogenetic disorder, characterized by hypermetabolic crisis triggered by halogenated anesthetics and/or succinylcholine. The standard method for diagnosing malignant hyperthermia susceptibility is the in vitro muscle contracture test in response to halothane-caffeine, which requires muscle biopsy under anesthesia. We describe a series of...

Date: 2019   |   Origin: Oasisbr

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