2 documents found, page 1 of 1
Early Versus Late Initiation of Direct Oral Anticoagulants in Post-Ischaemic St...
Fischer, U; Trelle, S; Branca, M; Salanti, G; Paciaroni, M; Ferrari, C; Abend, S; Beyeler, S; Strbian, D; Thomalla, G; Ntaios, G; Bonati, L; Michel, PRationale: Direct oral anticoagulants (DOAC) are highly effective in preventing ischaemic strokes in people with atrial fibrillation (AF). However, it is unclear how soon they should be started after acute ischaemic stroke (AIS). Early initiation may reduce early risk of recurrence but might increase the risk of haemorrhagic complications. Aim: To estimate the safety and efficacy of early initiation of DOACs co...
DisProt: Intrinsic protein disorder annotation in 2020
Hatos, A; Hajdu-Soltész, B; Monzon, AM; Palopoli, N; Álvarez, L; Aykac-Fas, B; Bassot, C; Benítez, GI; Bevilacqua, M; Chasapi, A; Chemes, L; Davey, NEThe Database of Protein Disorder (DisProt, URL: https://disprot.org) provides manually curated annotations of intrinsically disordered proteins from the literature. Here we report recent developments with DisProt (version 8), including the doubling of protein entries, a new disorder ontology, improvements of the annotation format and a completely new website. The website includes a redesigned graphical interfac...