Achondroplasia is the most common and most researched skeletal dysplasia. It is caused by a mutation in the fibroblast growth factor receptor 3 (FGFR3) gene, leading to abnormal endochondral ossification which causes multiple anatomical anomalies, the most characteristic being macrocephaly and asymmetrical short stature with proximal shortening of the limbs. The anatomical changes will result in organic and fun...
Ankle sprains are the most common injury in basketball, and the injury mechanism usually involved is the forced inversion of the foot during quick changes of direction, jump shots and/or physical contact between players. High-top basketball shoes began to be marketed under the premise that they ensure greater stabilization of the ankle joint and a consequent protective effect, but to date there is no evidence t...
Structural scoliosis is a deformity of the spine in all anatomical planes. The diagnosis is made when the lateral curvature in the frontal plane (Cobb angle) is equal or greater to 10o. Severe scoliosis can significantly impair the quality of life of these patients, leading to functional impairment, respiratory dysfunction and aesthetic changes with psychosocial impact. The main goal of the treatment is therefo...
Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina; Introdução: A lipoprotein-associated phospholipase A2 (Lp-PLA2) é um marcador inflamatório específico para o endotélio vascular, envolvido no processo de formação e destabilização da placa aterosclerótica que está na origem de síndromes coronários agudos (SCA). O objetivo deste trabalho é estabelecer uma relação entre os nívei...