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Worldwide experience of homozygous familial hypercholesterolaemia: retrospectiv...

Tromp, Tycho R.; Hartgers, Merel L.; Hovingh, G Kees; Vallejo-Vaz, Antonio J.; Ray, Kausik K.; Soran, Handrean; Freiberger, Tomas; Bertolini, Stefano

Background: Homozygous familial hypercholesterolaemia (HoFH) is a rare inherited disorder resulting in extremely elevated low-density lipoprotein cholesterol levels and premature atherosclerotic cardiovascular disease (ASCVD). Current guidance about its management and prognosis stems from small studies, mostly from high-income countries. The objective of this study was to assess the clinical and genetic charact...

Date: 2022   |   Origin: Repositório Científico do Instituto Nacional de Saúde
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2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein...

Landmesser, Ulf; Chapman, M. John; Stock, Jane K.; Amarenco, Pierre; Belch, Jill J. F.; Borén, Jan; Farnier, Michel; Ference, Brian A.; Gielen, Stephan

Date: 2018   |   Origin: Repositório da Universidade de Lisboa
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