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Changes in parental smoking during pregnancy and risks of adverse birth outcome...

Philips, EM; Santos, S; Trasande, L; Aurrekoetxea, JJ; Barros, H; von Berg, A; Bergström, A; Bird, PK; Brescianini, S; Ní Chaoimh, C; Charles, MA

Background. Fetal smoke exposure is a common and key avoidable risk factor for birth complications and seems to influence later risk of overweight. It is unclear whether this increased risk is also present if mothers smoke during the first trimester only or reduce the number of cigarettes during pregnancy, or when only fathers smoke. We aimed to assess the associations of parental smoking during pregnancy, spec...


Maternal body mass index, gestational weight gain, and the risk of overweight a...

Voerman, E; Santos, S; Patro Golab, B; Amiano, P; Ballester, F; Barros, H; Bergström, A; Charles, MA; Chatzi, L; Chevrier, C; Chrousos, GP

Maternal obesity and excessive gestational weight gain may have persistent effects on offspring fat development. However, it remains unclear whether these effects differ by severity of obesity, and whether these effects are restricted to the extremes of maternal body mass index (BMI) and gestational weight gain. We aimed to assess the separate and combined associations of maternal BMI and gestational weight gai...


Impact of maternal body mass index and gestational weight gain on pregnancy com...

Santos, S; Voerman, E; Amiano, P; Barros, H; Beilin, LJ; Bergström, A; Charles, MA; Chatzi, L; Chevrier, C; Chrousos, GP; Corpeleijn, E; Costa, O

Objective To assess the separate and combined associations of maternal pre-pregnancy body mass index (BMI) and gestational weight gain with the risks of pregnancy complications and their population impact. Design Individual participant data meta-analysis of 39 cohorts. Setting Europe, North America, and Oceania. Population 265 270 births. Methods Information on maternal pre-pregnancy BMI, gestational weight gai...


Gestational weight gain charts for different body mass index groups for women i...

Santos, S; Eekhout, I; Voerman, E; Gaillard, R; Barros, H; Charles, MA; Chatzi, L; Chevrier, C; Chrousos, GP; Corpeleijn, E; Costet, N; Crozier, S

BackgroundGestational weight gain differs according to pre-pregnancy body mass index and is related to the risks of adverse maternal and child health outcomes. Gestational weight gain charts for women in different pre-pregnancy body mass index groups enable identification of women and offspring at risk for adverse health outcomes. We aimed to construct gestational weight gain reference charts for underweight, n...


Mother's education and offspring asthma risk in 10 European cohort studies

Lewis, KM; Ruiz, M; Goldblatt, P; Morrison, J; Porta, D; Forastiere, F; Hryhorczuk, D; Zvinchuk, O; Saurel-Cubizolles, MJ; Lioret, S; Annesi-Maesano, I

Highly prevalent and typically beginning in childhood, asthma is a burdensome disease, yet the risk factors for this condition are not clarified. To enhance understanding, this study assessed the cohort-specific and pooled risk of maternal education on asthma in children aged 3–8 across 10 European countries. Data on 47,099 children were obtained from prospective birth cohort studies across 10 European countrie...


Impact of Low Maternal Education on Early Childhood Overweight and Obesity in E...

Ruiz, M; Goldblatt, P; Morrison, J; Porta, D; Forastiere, F; Hryhorczuk, D; Antipkin, Y; Saurel-Cubizolles, MJ; Lioret, S; Vrijheid, M; Torrent, M

BACKGROUND:Comparable evidence on adiposity inequalities in early life is lacking across a range of European countries. This study investigates whether low maternal education is associated with overweight and obesity risk in children from distinct European settings during early childhood. METHODS:Prospective data of 45 413 children from 11 European cohorts were used. Children's height and weight obtained at age...


Mother's education and the risk of preterm and small for gestational age birth:...

Ruiz, M; Goldblatt, P; Morrison, J; Kukla, L; Švancara, J; Riitta-Järvelin, M; Taanila, A; Saurel-Cubizolles, MJ; Lioret, S; Bakoula, C; Veltsista, A

Background A healthy start to life is a major priority in efforts to reduce health inequalities across Europe, with important implications for the health of future generations. There is limited combined evidence on inequalities in health among newborns across a range of European countries. Methods Prospective cohort data of 75 296 newborns from 12 European countries were used. Maternal education, preterm and sm...


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