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MIBiG 4.0: advancing biosynthetic gene cluster curation through global collabor...

Zdouc, Mitja M.; Blin, Kai; Louwen, Nico L. L.; Navarro, Jorge; Loureiro, Catarina; Bader, Chantal D.; Bailey, Constance B.; Barra, Lena

Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is governed by sets of co-regulated and physically clustered genes known as biosynthetic gene clusters (BGCs). To share information about BGCs in a standardized and machine-readabl...


Design and preparation of a novel colon-targeted tablet of hydrocortisone

Ren, Yachao; Jiang, Lei; Yang, Shuman; Gao, Sainan; Yu, Hui; Hu, Jie; Hu, Dandan; Mao, Wenbin; Peng, Haisheng; Zhou, Yulong

The objective of this research was to design a new colon-targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composite films were used in a bilayer system to investigate their feasibility as coating materials. Tensile strength, swelling degree, solubility, biodegradation degree, Fourier Tra...

Date: 2017   |   Origin: Oasisbr

Design and preparation of a novel colon-targeted tablet of hydrocortisone

Ren, Yachao; Jiang, Lei; Yang, Shuman; Gao, Sainan; Yu, Hui; Hu, Jie; Hu, Dandan; Mao, Wenbin; Peng, Haisheng; Zhou, Yulong

The objective of this research was to design a new colon-targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composite films were used in a bilayer system to investigate their feasibility as coating materials. Tensile strength, swelling degree, solubility, biodegradation degree, Fourier tra...

Date: 2016   |   Origin: Oasisbr

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