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Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysi...

Robinson, L; Roccaldo, R; Rodrigues, D; Rodriguez Perez, MdC; Rodríguez Villamizar, LA; Rodríguez, AY; Roggenbuck, U; Rohloff, P; Rohner, F

Background: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods: We used data from 3663 population-based studies with 222 million participants that...


Height and body-mass index trajectories of school-aged children and adolescents...

Horimoto, AR; Hormiga, CM; Horta, BL; Houti, L; Howitt, C; Htay, TT; Htet, AS; Htike, MMT; Hu, Y; Huerta, JM; Huhtaniemi, IT; Huidumac Petrescu, C

Background: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods: For this pooled analysis, we used a database of cardiometabolic risk factors colla...


Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-ba...

Zhou, B; Lu, Y; Hajifathalian, K; Bentham, J; Di Cesare, M; Danaei, G; Bixby, H; Cowan, MJ; Ali, MK; Taddei, C.; Lo, WC; Ninomiya, T; Noale, M; Noto, D

Background One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the age standardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are aff ecting the number of adults with diabetes. Method...


A Novel Autosomal Recessive GJA1 Missense Mutation Linked to Craniometaphyseal ...

Hu, Y; Chen, I; Almeida, S; Tiziani, V; Amaral, C; Gowrishankar, K; Passos-Bueno, MR; Reichenberger, E

Craniometaphyseal dysplasia (CMD) is a rare sclerosing skeletal disorder with progressive hyperostosis of craniofacial bones. CMD can be inherited in an autosomal dominant (AD) trait or occur after de novo mutations in the pyrophosphate transporter ANKH. Although the autosomal recessive (AR)form of CMD had been mapped to 6q21-22 the mutation has been elusive. In this study, we performed whole-exome sequencing f...


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