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Exploratory evidence for differences in GABAergic regulation of auditory proces...

Huang, Qiyun; Velthuis, Hester; Pereira, Andreia C.; Ahmad, Jumana; Cooke, Samuel F.; Ellis, Claire L.; Ponteduro, Francesca M.; Puts, Nicolaas A. J.

Altered reactivity and responses to auditory input are core to the diagnosis of autism spectrum disorder (ASD). Preclinical models implicate ϒ-aminobutyric acid (GABA) in this process. However, the link between GABA and auditory processing in humans (with or without ASD) is largely correlational. As part of a study of potential biosignatures of GABA function in ASD to inform future clinical trials, we evaluated...


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