25 documents found, page 1 of 3

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Combined action of dietary-based approaches and therapeutic agents on cholester...

Baptista, Eugénia; Pereira, Cláudia S.G.P.; García, Pablo A.; Ferreira, Isabel C.F.R.; Barreira, João C.M.

Dyslipidaemia is among the major causes of severe diseases and, despite being wellestablished, the hypocholesterolaemic therapies still face significant concerns about potential side effects (such as myopathy, myalgia, liver injury digestive problems, or mental fuzziness in some people taking statins), interaction with other drugs or specific foods. Accordingly, this review describes the latest developments in ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Chemical and Bioactive Properties of Red Rice with Potential Pharmaceutical Use

Baptista, Eugénia; Liberal, Ângela; Cardoso, Rossana V.C.; Fernandes, Ângela; Dias, Maria Inês; Pires, Tânia C.S.P.; Calhelha, Ricardo C.

Red rice has been proposed as a super-food. Accordingly, the nutritional properties (AOAC), as well as its chemical composition, including sugars (HPLC-RI), organic acids (UFLC-PDA), tocopherols (HPLD-FD), and phenolic compounds (LC-DAD-ESI/MSn), together with the main bioactive properties (antioxidant, cytotoxic, antiproliferative, and antibacterial activities), were evaluated to access its nutritional benefit...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Response surface methodology applied to ultrasound-assisted extraction of raspb...

Plasencia, Paula; Carocho, Márcio; Heleno, Sandrina A.; Finimundy, Tiane C.; Barreiro, M.F.; García, Pablo A.; Barros, Lillian

Due to their high nutritional value, berries production has increased, but this inevitably leads to the accumulation of bioresidues. To prevent this, leaves and other aerial components of berry plants can be converted into valuable ingredients for cosmetics applications due to their unique chemical composition and functional properties. Ultrasound-assisted extraction methodology is an efficient technique to obt...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Unveiling the metabolites underlying the skin anti-ageing properties of Cytinus...

Silva, Ana Rita; Ayuso, Manuel; García, Pablo A.; Barros, Lillian; Edrada-Ebel, RuAngelie

The genus Cytinus, recognised as one of the most enigmatic in the plant kingdom, has garnered attention for its bioactive potential, particularly its skin anti-ageing properties. Despite this recognition, much remains to be accomplished regarding deciphering and isolating its most active compounds. Hypothesis: This study aimed to identify the compounds responsible for C. hypocistis skin anti-ageing potential. M...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Screening of antioxidant effect of spontaneous and bioinoculated with gluconoba...

Leitão, Mariana; Ferreira, Beatriz; Guedes, Beatriz; Moreira, Daniela; García, Pablo A.; Barreiros, Luísa; Correia, Patrícia Carla dos Santos

Fermented papaya is recognized as a nutraceutical with a diverse and rich composition. Fermentation of fruit with desirable microorganisms could be a strategy to improve the nutritional quality and profile of the fruit. Despite the popularity of fermented papaya, there is still a lack of knowledge on the effects of various fermentation parameters. The goal of this study was to screen the antioxidant and other p...


Cytinus hypocistis (L.) L. and its great bioactive potential

Silva, Ana Rita; García, Pablo A.; Ferreira, Isabel C.F.R.; Barros, Lillian

Plant-derived compounds have been extensively investigated to find novel active compounds as templates to mitigate the relative void of combinatorial chemistry, offering the potential to discover innovative structures that can lead to effective agents for various purposes [1]. Cytinus hypocistis (L.) L. is a wild edible parasitic plant on numerous members of the Cistaceae family. Although its biological propert...

Date: 2022   |   Origin: Biblioteca Digital do IPB

Evaluation of parasite and host phenolic composition and bioactivities − The pr...

Silva, Ana Rita; Ayuso, Manuel; Pereira, Carla; Dias, Maria Inês; Kostić, Marina; Calhelha, Ricardo C.; Soković, Marina; García, Pablo A.

Cytinus hypocistis (L.) L. is a comestible holoparasite with great potential for cosmeceutical application. Although its high tannin content has been associated with its bioactive and inhibitory enzyme properties, this is the first report establishing a relationship between parasite and host (Halimium lasianthum (Lam.) Greuter) phenolic profile and bioactive properties. Thus, five extracts (aerial and root extr...

Date: 2022   |   Origin: Biblioteca Digital do IPB

Metabolomic approach to assess the effect of the foraging year on the anti-elas...

Silva, Ana Rita; Ayuso, Manuel; García, Pablo A.; Barros, Lillian; Edrada-Ebel, RuAngelie

Cytinus hypocistis (L.) L. is a wild edible parasitic plant on numerous members of the Cistaceae family. Although its bioactive properties were potentially attributed to its hydrolysable tannin content, its chemical composition is largely unknown, and the bioactive substances have not yet been identified [1,2]. Thus, this work aimed to investigate its potential to inhibit human elastase, an important anti-agein...

Date: 2022   |   Origin: Biblioteca Digital do IPB

Benefits of fermented papaya in human health

Leitão, Mariana; Ribeiro, Tatiana; García, Pablo A.; Barreiros, Luísa; Correia, Patrícia Carla dos Santos

Fermented foods have been used for several years all over the world, due to their unique nutritional characteristics and because fermentation promotes conservation and food security. More over, fermented foods and beverages have a strong impact on human gut microbiota. Papaya is the fruit of the Carica papaya plant, traditionally used as a medicinal fruit, but there are also references to the use of the ferment...


Cytinus hypocistis (L.) L.: optimised heat/ultrasound-assisted extraction of ta...

Silva, Ana Rita; Pinela, José; García, Pablo A.; Ferreira, Isabel C.F.R.; Barros, Lillian

Tannins are a class of phenolic compounds commonly found in plants and studied for their bioactive and inhibitory enzyme properties. Cytinus hypocistis (L.) L. is a wild edible parasitic plant whose biological properties have been correlated with its high tannin content. Thus, studying the extraction of tannins from C. hypocistis will give comprehensive clues to enhance the recovery of these high added-value bi...

Date: 2021   |   Origin: Biblioteca Digital do IPB

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