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The effect of synthetic cannabinoid ADB-FUBINACA on primary neuronal cultures ß...

Roque-Bravo, Rita; Carmo, Helena; Silva, João Pedro; Carvalho, Félix; Dias-da-Silva, Diana

Background: ADB-FUBINACA (ADB-FUB) is a synthetic cannabinoid (SC) that has gained popularity among users as a new psychoactive substance. This stems from SC's pharmacological similarity to the active principle of cannabis, D9-tetrahydrocannabinol (THC). However, unlike THC, SCs demonstrate full agonism of cannabinoid receptors 1 and 2 [1]. Recent scientific developments have shown that cannabis use m...

Date: 2024   |   Origin: Scientific Letters

Drug use among the student population of the University of Porto: Analysis of p...

Garcia, Helena Rafaela; Roque-Bravo, Rita; Dias-da-Silva, Diana

Background: Alcohol, tobacco, and illicit drugs use by university students is a complex issue that has garnered concern and interest from public health officials, educators, and scientific community [1]. This concern is driven by various factors, including the potential to affect academic performance and mental and physical health. Objective: This study was designed to determine the prevalence and patterns of p...

Date: 2024   |   Origin: Scientific Letters

Chemical characterization and in vitro studies on the impact of the 'Dream Herb...

Garcia, Maria Rita; Mineiro, Tiago; Andrade, Paula B.; Ferreres, Federico; Gil-Izquierdo, Ángel; Seabra, Vítor; Dias-da-Silva, Diana

Background: An increasing number of psychoactive plants, particularly those with long history of use on ritualistic practices, are now being progressively used in recreational context, many of which remaining unregulated [1]. Calea zacatechichi is traditionally used in divination rituals, due to its oneirogenic properties. Yet, considering the psychoactive effects of this ‘Dream Herb’ and easiness of purchase, ...

Date: 2024   |   Origin: Scientific Letters

Preliminary chemical profile and in vitro pharmacological evaluation of the hal...

Garcia, Maria Rita; Dutka, Mykhaylo; Guimarães, Sofia; Andrade, Paula B.; Seabra, Vítor; Dias-da-Silva, Diana

Background: For the last few years, Ayahuasca ceremonies have been gaining popularity in recreational settings in Europe and North America [1]. Similar to Psychotria viridis, Diplopterys cabrerana is also suggested to contain the psychoactive compound N,N-dimethyltryptamine, and is therefore used in Ayahuasca rituals for its ability to induce hallucinations, euphoria and entheogenic effects [1-3]. However, whil...

Date: 2024   |   Origin: Scientific Letters

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