7 documents found, page 1 of 1
DNA content evaluation for epithelial ovarian cancer identification
Tomé, António; Leal, Irene; Palmeiras, Carlos; Matos, Eduarda; Amado, João; Abreu, Miguel; Lopes, CarlosObjective: To assess the cellular DNA status of epithelial ovarian cancer cells for clinical stage identification and its effect on survival. Methods: Sixty-twopatients treated by primary surgery and six courses of platinum-based chemotherapy were enrolled. The surgical stage was analyzed in correlation with DNA ploidy, S-phase fraction and DNA index. DNA analysis was performed via image cytometry. Results: Fro...
Improving malignancy prediction in breast lesions with the combination of appar...
Nogueira, Luisa; Brandão, Sofia; Matos, Eduarda; Gouveia Nunes, Rita; Ferreira, Hugo Alexandre; Loureiro, Joana; Ramos, IsabelAim To assess how the joint use of apparent diffusion coefficient (ADC) and kinetic parameters (uptake phase and delayed enhancement characteristics) from dynamic contrast-enhanced (DCE) can boost the ability to predict breast lesion malignancy. Materials and methods Breast magnetic resonance examinations including DCE and diffusion-weighted imaging (DWI) were performed on 51 women. The association between kine...
Fat suppression techniques (STIR vs. SPAIR) on diffusion-weighted imaging of br...
Brandão, Sofia; Nogueira, Luísa; Matos, Eduarda; Nunes, Rita Gouveia; Ferreira, Hugo Alexandre; Loureiro, Joana; Ramos, IsabelPurpose The aim of this work was to perform a qualitative and quantitative comparison of the performance of two fat suppression techniques on breast diffusion-weighted imaging (DWI). Materials and methods Fifty-one women underwent clinical breast magnetic resonance imaging, including DWI with short TI inversion recovery (STIR) and spectral attenuated inversion recovery (SPAIR). Four were excluded from the analy...
Region of interest demarcation for quantification of the apparent diffusion coe...
Nogueira, Luísa; Brandão, Sofia; Matos, Eduarda; Nunes, Rita Gouveia; Ferreira, Hugo Alexandre; Loureiro, Joana; Ramos, IsabelPURPOSE We aimed to compare two different methods of region of interest (ROI) demarcation and determine interobserver variability on apparent diffusion coefficient (ADC) in breast lesions. METHODS Thirty-two patients with 39 lesions were evaluated with a 3.0 Tesla scanner using a diffusion-weighted sequence with several b-values. Two observers independently performed the ADC measurements using: 1) a small fixed...
Application of the diffusion kurtosis model for the study of breast lesions
Nogueira, Luísa; Brandão, Sofia; Matos, Eduarda; Nunes, Rita Gouveia; Loureiro, Joana; Ramos, Isabel; Ferreira, Hugo AlexandreObjectives To evaluate diffusion-weighted imaging (DWI) and diffusion kurtosis imaging (DKI) in the differentiation and characterisation of breast lesions. Methods Thirty-six women underwent breast magnetic resonance imaging (MRI) including a DWI sequence with multiple b-values (50–3,000 s/mm2). Mean values for apparent diffusion coefficient (ADC), mean diffusivity (MD) and mean kurtosis (MK) were calculated by...
Intra and extra-familiar sexual abuse.
Taveira, Francisco; Frazão, Sofia; Dias, Ricardo; Matos, Eduarda; Magalhães, TeresaThe sexual abuse of a child or young person constitutes a major social and public health problem and there is recent evidence that intra-familial (IF) sexual abuses are more serious in their consequences than extra-familial (EF). However, there are no studies on this phenomenon in Portugal. Thus, the aim of the present study is to contribute to a better characterization of these types of abuses and to identify ...
Efficacy, safety and long-term follow-up of laparoscopic Heller’s myotomy with ...
Nogueira, Carlos; Santos, Jorge Nunes; Marcos, Mário Sérgio; Matos, EduardaThe primary indication for esophagocardiomiotomy at our institution over the last 12 years has been failure of endoscopic balloon dilation with consequent persistence of dysphagia or intra-procedure viscus perforation. In 1996 we began using a laparoscopic approach for esophagocardiomiotomy, thereby offering our patients a minimally invasive alternative to endoscopic dilation. Materials and Methods: We reviewed...