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An integrative approach to characterize the early phases of dimethylhydrazine-i...

Silva-Reis, Carla; Castro-Ribeiro, C; Gonçalves, M; Ferreira, T; Pires, MJ; Iglesias-Aguirre, CE; Cortés-Martín, A; Selma, MV; Espín, JC

This study aimed to characterize an animal model of colorectal cancer (CRC) in the early stages of disease development. Twenty-nine male Wistar rats were divided into two control groups (CTRL1 and CTRL2), receiving EDTA–saline injections and two induced groups (CRC1 and CRC2), receiving 1,2-dimethylhydrazine (DMH) injections for seven consecutive weeks. CRC1 and CTRL1 were euthanized at the 11th week, while CRC...

Date: 2022   |   Origin: Repositório Científico da Universidade de Évora
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