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Primary Central Nervous System Lymphoma Mimicking Neuro-Behcet Disease

Silva, Lénia; Costa, Sara; Igreja, Liliana; Taipa, Ricardo; Araújo Correia, João; Santos, Ernestina

Neuro-Behcet’s disease (NBD) and primary central nervous system lymphoma (PCNSL) are rare conditions that can present with overlapping features, often delaying diagnosis. We report a female patient with recurrent oral aphthae and arthralgia who developed visual disturbances, behavioral changes, and hemiparesis. Brain magnetic resonance imaging (MRI) showed multiple contrast-enhancing lesions, and cerebrospinal ...

Date: 2026   |   Origin: SINAPSE

A 30-year experience in neuro-Behçet disease

Silva, Lénia; Silva, Isabel Fonseca; Fonseca, Tomás; Pinto, Luísa Serpa; Leal, Bárbara; Pinho e Costa, Paulo; Igreja, Liliana; Moreira, Bruno

Background: Behçet disease (BD) is a systemic vasculitis affecting multiple organs with a wide range of severity. Neuro-Behçet (NBD) is a severe form, characterized by high morbidity, disability, and mortality rates. Methods: Retrospective analysis (1993-2023) of neurological involvement in BD patients at a tertiary center. Results: Of 296 BD patients, 93(31.4 %) underwent neurological evaluation. Definite NBD ...


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