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Differences in coping strategies in adult patients with bipolar disorder and th...

Bridi,Kelen Patrícia Bürke; Loredo-Souza,Ana Claudia M.; Fijtman,Adam; Moreno,Mirela Vasconcelos; Kauer-Sant'Anna,Márcia; Ceresér,Keila Maria Mendes

Abstract Introduction: The objective of this study was to compare patients with bipolar disorder (BD), their first-degree relatives and a group of healthy controls in terms of use of adaptive and maladaptive coping strategies, exploring differences between specific types of strategies and their correlations with clinical variables. Methods: This was a cross-sectional study enrolling 36 euthymic patients with BD...

Date: 2018   |   Origin: Oasisbr

Cognitive performance and psychosocial functioning in patients with bipolar dis...

Vasconcelos-Moreno,Mirela P.; Bücker,Joana; Bürke,Kelen P.; Czepielewski,Leticia; Santos,Barbara T.; Fijtman,Adam; Passos,Ives C.; Kunz,Mauricio

Objective: To assess cognitive performance and psychosocial functioning in patients with bipolar disorder (BD), in unaffected siblings, and in healthy controls. Methods: Subjects were patients with BD (n=36), unaffected siblings (n=35), and healthy controls (n=44). Psychosocial functioning was accessed using the Functioning Assessment Short Test (FAST). A sub-group of patients with BD (n=21), unaffected sibling...

Date: 2016   |   Origin: Oasisbr

Biomarkers and staging of bipolar disorder: a systematic review

Roda,Ângela; Chendo,Inês; Kunz,Mauricio

INTRODUCTION: A growing body of evidence suggests that bipolar disorder (BD) is a progressive disease according to clinical, biochemical and neuroimaging findings. This study reviewed the literature on the relationship between specific biomarkers and BD stages.METHODS: A comprehensive literature search of MEDLINE and PubMed was conducted to identify studies in English and Portuguese using the keywords biomarker...

Date: 2015   |   Origin: Oasisbr

Pharmacological treatment and staging in bipolar disorder: evidence from clinic...

Goi,Pedro D.; Bücker,Joana; Vianna-Sulzbach,Mireia; Rosa,Adriane R.; Grande,Iria; Chendo,Ines; Sodré,Leonardo A.; Kauer-Sant'Anna,Marcia

Objectives:Staging models for medical diseases are widely used to guide treatment and prognosis. Bipolar disorder (BD) is a chronic condition and it is among the most disabling disorders in medicine. The staging model proposed by Kapczinski in 2009 presents four progressive clinical stages of BD. Our aim was to evaluate pharmacological maintenance treatment across these stages in patients with BD.Methods:One hu...

Date: 2015   |   Origin: Oasisbr

Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and sch...

Kunz,Mauricio; Ceresér,Keila Maria; Goi,Pedro Domingues; Fries,Gabriel Rodrigo; Teixeira,Antonio L.; Fernandes,Brisa Simões

OBJECTIVE: Previous reports suggest that cytokines act as potential mediators of the interaction between the immune and neuroendocrine systems, and that a proinflammatory state may be associated with bipolar disorder and schizophrenia. The aim is to compare cytokine levels in both disorders. METHOD: Twenty euthymic bipolar disorder patients, 53 chronic stabilized schizophrenia patients and 80 healthy controls w...

Date: 2011   |   Origin: Oasisbr

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