5 documents found, page 1 of 1
Chronic thromboembolic pulmonary hypertension: a comprehensive review of pathog...
Cazeiro, Daniel; Azaredo Raposo, Miguel; Guimarães, Tatiana; Lousada, Nuno; Jenkins, David; Inácio, João R.; Moreira, Susana; Mineiro, AnaChronic thromboembolic pulmonary hypertension (CTEPH) is part of group 4 of the pulmonary hypertension (PH) classification and generally affects more than a third of patients referred to PH centers. It is a three-compartment disease involving proximal (lobar-to-segmental) and distal (subsegmental) pulmonary arteries that are obstructed by persistent fibrothrombotic material, and precapillary pulmonary arteries ...
Multidimensional CT approach to predict hemodynamics in pulmonary hypertension
Brito, Joana; Alves da Silva, Pedro; Cazeiro, Daniel; Azaredo Raposo, Miguel; Lousada, Nuno; Inácio, João R.; Guimarães, Tatiana; Almeida, Ana G.Aim: Computed tomographic pulmonary angiography (CTPA) allows an excellent visualization of heart chambers and vessels, which may be associated with hemodynamic status in pulmonary hypertension, obviating the need for repetitive right heart catheterization (RHC). In this study, we aimed to evaluate the capacity of CTPA to predict severe hemodynamics and to correlate with clinical status and events. Material and...
Epipericardial fat necrosis in chest CT and MRI: a case report of an unusual ca...
Barreto, Inês; Oliveira, Francisca Godinho; Barreira, Sofia; Inácio, João R.Background: Epipericardial fat necrosis (EFN) is a benign and self-limited condition of unknown cause with a good prognosis, usually affecting otherwise healthy patients. Clinically, it presents with severe acute left pleuritic chest pain, often leading the patient to the Emergency Room (ER). Case presentation: A 23-year-old male, smoker (5 pack-years), was evaluated in the ER due to left pleuritic chest pain, ...
Phenotype of BTK‐lacking myeloid cells during prolonged COVID‐19 and upon conva...
Gomes, André; Farias, Guilherme B.; Trombetta, Amelia Chiara; Godinho-Santos, Ana; Parreira, Inês; Gonçalves, Hélder Diogo; Lessa Simões, MarianaXLA patient with 7-month course of COVID-19 with persistent plasma SARS-CoV-2 load revealed a sustained non-inflammatory profile of myeloid cells in association with contained severity of disease, arguing in favor of the use of BTK inhibitors in SARS-COV-2 infection.
Posterior reversible encephalopathy syndrome and digital gangrene in a patient ...
Martins, Patrícia; Valido, Ana; Melo, Ana Teresa; Santareno, Sofia; Sousa, Rita; Inácio, João R.; Oliveira-Ramos, Filipa; Ponte, Cristina; Romeu, JoséGranulomatosis with Polyangiitis (GPA) is an antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis(AAV), classically associated with the presence of proteinase 3 (PR3)-ANCA. GPA has a wide range of clinical manifestations, with multiorgan involvement, particularly upper and lower respiratory tract, and kidneys. One of itsrarest manifestationsis digital ischemia or gangrene that accounts for <1% of ca...