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Comorbidities, timing of treatments, and chemotherapy use influence outcomes in...

Minicozzi, P; Vicentini, M; Innos, K; Castro, C; Guevara, M; Stracci, F; Carmona-Garcia, M; Rodriguez-Barranco, M; Vanschoenbeek, K; Rapiti, E

Introduction For stage III colon cancer (CC), surgery followed by chemotherapy is the main curative approach, although optimum times between diagnosis and surgery, and surgery and chemotherapy, have not been established. Materials and methods We analysed a population-based sample of 1912 stage III CC cases diagnosed in eight European countries in 2009–2013 aiming to estimate: (i) odds of receiving postoperative...


The global burden of childhood and adolescent cancer in 2017: an analysis of th...

Force, LM; Abdollahpour, I; Advani, SM; Agius, D; Ahmadian, E; Alahdab, F; Alam, T; Alebel, A; Alipour, V; Allen, CA; Almasi-Hashiani, A; Alvarez, EM

Background Accurate childhood cancer burden data are crucial for resource planning and health policy prioritisation. Model-based estimates are necessary because cancer surveillance data are scarce or non-existent in many countries. Although global incidence and mortality estimates are available, there are no previous analyses of the global burden of childhood cancer represented in disability-adjusted life-years...


Comorbidities, age and period of diagnosis influence treatment and outcomes in ...

Minicozzi, P; Van Eycken, L; Molinie, F; Innos, K; Guevara, M; Marcos-Gragera, R; Castro, C; Rapiti, E; Katalinic, A; Torrella, A; Žagar, T

Survival for breast cancer (BC) is lower in eastern than northern/central Europe, and in older than younger women. We analysed how comorbidities at diagnosis affected whether selected standard treatments (STs) were given, across Europe and over time, also assessing consequences for survival/relapse. We analysed 7581 stage I/IIA cases diagnosed in 9 European countries in 2009–2013, and 4 STs: surgery; breast-con...


Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost,...

Fitzmaurice, C; Akinyemiju, T; Al Lami, F; Alam, T; Alizadeh-Navaei, R; Allen, C; Alsharif, U; Alvis-Guzman, N; Amini, E; Anderson, B; Aremu, O

Importance: The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments...


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