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Spontaneous co-assembly of molecularly designed building blocks into hierarchic...
Smith, K. H.; Inostroza, K. E.; Alonso, Matilde; Reis, R. L.; Azevedo, Helena S.; Mata, A.A major limitation in generating materials using bottom-up strategies is the lack of order at the macroscale. In this work, we show that two self-assembling molecules, an elastin-like polymer (ELP) and a peptide amphiphile (PA), can interact to spontaneously to form hierarchically ordered, dynamic, bioactive, macrotubes. An RGD-containing ELP and a PA (C16V3A3K3) were synthesised using standard methods. The add...
Date: 2012
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Origin: RepositóriUM - Universidade do Minho