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Para Além da Falta de Iodo: O Papel do Ambiente no Hipotiroidismo

Coelho, Nádia; Garcia, Patrícia; Rodrigues, Armindo

A tiroide é uma glândula do sistema endócrino em forma de borboleta situada na parte anterior do pescoço, logo à frente da traqueia (figura 1). Esta glândula encarrega-se de produzir as hormonas tetraiodotironina (tiroxina ou T4) e triiodotironina (T3). As hormonas da tiroide atuam sobre vários aspetos do metabolismo: questões como o desenvolvimento neuronal, ritmo cardíaco, ritmo respiratório, função muscular,...


Leptospirose: o inimigo invisível

Camarinho, Ricardo; Rodrigues, Armindo

A leptospirose (também chamada doença de Weil) é uma zoonose bacteriana causada por espiroquetas patogénicas do género Leptospira. É uma doença com elevado impacto global que infecta humanos e animais. Relativamente ao impacto humano, estima-se que esta zoonose seja mundialmente responsável por cerca de 1 milhão de casos anuais, causando cerca de 60.000 mortes. A infeção pode ocorrer diretamente através de cont...


Histological evidence of hypothyroidism in mice chronically exposed to conventi...

Coelho, Nádia; Camarinho, Ricardo; Garcia, Patrícia; Rodrigues, Armindo

Worldwide, disorders of the thyroid gland are a growing concern; such can be caused by exposure to contaminants, including agrochemicals used in conventional agriculture, which act as endocrine disruptors. The purpose of this study is to evaluate whether or not exposure to an environment with conventional agriculture leads to thyroid disruption. Mus musculus were used as bioindicator species, captured in two si...


Exposição crónica a mercúrio vulcânico e efeitos na saúde.

Rodrigues, Armindo; Garcia, Patrícia

O mercúrio (Hg) é um metal pesado que ocorre naturalmente no ambiente, sendo o único que, à temperatura ambiente, se encontra no estado líquido. Pode ser encontrado nas formas químicas elementar (Hg0) inorgânica, e orgânica, ligado a radicais de carbono, como por exemplo o metilmercúrio. A exposição crónica ao mercúrio, devido aos seus efeitos neurotóxicos, pode afetar o funcionamento do sistema nervoso, inicia...


Air Quality at Ponta Delgada City (Azores) Is Unaffected so Far by Growing Crui...

Bernardo, Filipe; Garcia, Patrícia; Rodrigues, Armindo

The ease of travel allowed by contemporary means of long-range transportation has brought increasingly higher numbers of visitors to remote and relatively undisturbed insular territories. In a framework of environmental conservation of the natural patrimony, sustainably accommodating touristic flooding and the associated polluting footprint poses a demanding challenge. Over the past decade, Ponta Delgada, the l...


Evaluation of Respiratory, Genotoxic and Cytotoxic Effects from Occupational Ex...

Linhares, Diana P.; Rocha, Joana Gonçalves; Rodrigues, Armindo; Camarinho, Ricardo; Garcia, Patrícia

This cross-sectional study was structured to allow the evaluation of the respiratory, genotoxic, and cytotoxic effects of occupational exposure to products resulting from the activity of printers in typographies and, to determine the risk of genotoxicity associated with such exposure. This study comprised 69 subjects, 25 individuals occupationally exposed to the products of typographies (study group), and 44 in...


Dendrochronological potential of the Azorean endemic gymnosperm Juniperus brevi...

Pavão, Diogo Cláudio; Jevšenak, Jernej; Petrillo, M.; Camarinho, Ricardo; Rodrigues, Armindo; Silva, L. Borges; Elias, Rui B.; Silva, Luís

Tree-ring inter-annual pattern variation is crucial in dendrochronology, allowing the identification of possible limiting factors on growth. Thus, trees exposed to subtropical or tropical climates without a marked seasonality may show a low degree of interannual variation, impeding a straightforward dendroclimatological approach. Meanwhile, subtropical regions, and areas in transitional climates such as the Azo...


Epithelial morphometric alterations and mucosecretory responses in the nasal ca...

Camarinho, Ricardo; Pardo, A. Madrero; Garcia, Patrícia; Rodrigues, Armindo

Air pollutants (either of natural or anthropogenic origin) represent a considerable environmental risk to human health by affecting the respiratory system and causing respiratory disorders. In this study, we investigate the effects of chronic exposure to hydrothermal emissions on the nasal cavity of mice since it is the first and the most exposed region of the respiratory system. This study, carried in S. Migue...


Drinking Bottled and Tap Water for Healthier Living in Volcanic Areas : Are All...

Linhares, Diana P.; Gaspar, Diogo; Garcia, Patrícia; Rodrigues, Armindo

In most volcanic areas, the population considers the use of bottled waters as a healthier and safer option. This study aimed to (i) assess the fluoride concentrations in tap and bottled water consumed on São Miguel Island, (ii) confirm the accuracy of the labeling of fluoride levels on bottled water, and (iii) assess the fluoride daily intake and risk exposure and discuss the possible health effects in adults a...


Iodine Intake and Related Cognitive Function Impairments in Elementary Schoolch...

Bailote, Helga G. B.; Linhares, Diana P.; Carvalho, Célia; Prazeres, Susana; Rodrigues, Armindo; Garcia, Patrícia

Iodine deficiency, the most common cause of preventable mental impairment worldwide, has been linked to poorer intellectual function in several studies. However, to our knowledge, no studies have been performed in moderate iodine-deficient schoolchildren using the complete form of Wechsler Intelligence Scale for Children (WISC-III; Portuguese version). The main purpose of this study was to ascertain whether mod...


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