3 documents found, page 1 of 1
Rotavirus alphagastroenteritidis
Vita, Dikudila G.; Santiso-Bellón, Cristina; Lemos, Manuel; Neto, Zoraima; Fortes-Gabriel, Elsa; Brito, Miguel; Sebastião, Cruz S.Funding Information: This research was funded by Abbott Rapid Diagnostics Group, the National Health Research Institute (INIS), Luanda, Angola, the Centro de Investigac & atilde;o em Saude de Angola (CISA), Angola, and the Gulbenkian Foundation, Lisbon, Portugal. The study sponsors had no role in the design of this study. Publisher Copyright: © 2025 by the authors.; Rotavirus alphagastroenteritidis (R. alphagas...
Characterization of rotavirus infection in children with acute gastroenteritis ...
Gasparinho, Carolina; Piedade, João; Mirante, Maria Clara; Mendes, Cristina; Mayer, Carlos; Nery, Susana Vaz; Brito, Miguel; Istrate, ClaudiaBackground: Rotavirus group A (RVA) is considered the leading cause of pediatric diarrhea, responsible for the high burden of diarrheal diseases in sub-Saharan Africa. Despite recent studies, the existent data are scarce for some African countries like Angola, a country with one of the highest RVA-related death estimates. The aim of this study was to determine the RVA detection rate and circulating genotypes in...
Rotavirus stimulates release of serotonin (5-HT) from human enterochromaffin ce...
Hagbom, Marie; Istrate, Claudia; Engblom, David; Karlsson, Thommie; Rodriguez-Diaz, Jesus; Buesa, Javier; Taylor, John A.; Loitto, Vesa MattiRotavirus (RV) is the major cause of severe gastroenteritis in young children. A virus-encoded enterotoxin, NSP4 is proposed to play a major role in causing RV diarrhoea but how RV can induce emesis, a hallmark of the illness, remains unresolved. In this study we have addressed the hypothesis that RV-induced secretion of serotonin (5-hydroxytryptamine, 5-HT) by enterochromaffin (EC) cells plays a key role in th...