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Rotavirus alphagastroenteritidis: circulating strains after the introduction of...

Vita, Dikudila G.; Santiso-Bellón, Cristina; Lemos, Manuel; Neto, Zoraima; Fortes-Gabriel, Elsa; Brito, Miguel; Sebastião, Cruz S.

Rotavirus alphagastroenteritidis (R. alphagastroenteritidis) remains the leading cause of pediatric diarrhea. Although Angola introduced Rotarix®, the human monovalent R. alphagastroenteritidis vaccine since 2014 as part of its routine childhood immunization program, no follow-up study has been conducted. This study aimed to evaluate the distribution of R. alphagastroenteritidis genotypes among children under f...


Characterization of rotavirus infection in children with acute gastroenteritis ...

Gasparinho, Carolina; Piedade, João; Mirante, Maria Clara; Mendes, Cristina; Mayer, Carlos; Nery, Susana Vaz; Brito, Miguel; Istrate, Claudia

Rotavirus group A (RVA) is considered the leading cause of pediatric diarrhea, responsible for the high burden of diarrheal diseases in sub-Saharan Africa. Despite recent studies, the existent data are scarce for some African countries like Angola, a country with one of the highest RVA-related death estimates. The aim of this study was to determine the RVA detection rate and circulating genotypes in children le...


Etiology of diarrhea in children younger than 5 years attending the Bengo Gener...

Gasparinho, Carolina; Mirante, Clara; Centeno-Lima, Sónia; Istrate, Claudia; Mayer, Carlos; Tavira, Luis; Nery, Susana Vaz; Brito, Miguel

Background - Diarrheal disease is among the leading causes of death in children younger than 5 years, especially in developing countries. The aim of this study was to investigate the most frequent etiological agents of diarrhea and its associated factors in children younger than 5 years attending the Bengo General Hospital in Angola. Methods - From September 2012 through December 2013, stool samples were collec...


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