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Pathogenic profile of a rabies virus isolated from an insectivorous bat Lasiurus ega was compared with a rabies fixed virus strain (CVS/32) in hamster and mouse. Incubation and clinical periods, clinical manifestation and death rates were compared. Challenge of hamsters with L. ega was performed using: 10 2,611-4,021 LD50 /0,05 mL;. For CVS were used 10 3,7- 4,7 LD50 /0,05 mL. Were tested intramuscular (IM), in...
O presente trabalho visou estudar dez isolados de vírus da raiva de morcegos hematófagos e não-hematófagos do Estado do Rio de Janeiro em suas características genéticas quanto aos genes N e G. Além disso, estudou-se a resposta de camundongos vacinados com a vacina antirrábica produzida pela replicação da amostra Pitman-Moore em cultivo celular, frente ao desafio com estes isolados virais, utilizando-se um ensai...
In vampire bats, food sharing behavior would contribute for the oral transmission of rabies virus among the roostmates. To test this hypothesis, 10 captive Desmodus rotundus bats were fed defibrinated swine blood containing mice brain suspension of PV-strain of rabies virus. Other 10 bats were fed blood mixed with a mice brain suspension of T-9/95 vampire-bat-field isolate of rabies virus. Another group of 10 b...
Nineteen kittens divided into four groups were fed with brains of mice infected with rabies viruses. Each four kittens (group I) received four brains infected with the PV fixed strain; nine kittens (group II) ingested 4-5 brains infected with the field isolate T-9/95, isolated from the Desmodus rotundus vampire bat; two kittens (group III) fed ten T-9/95-infected brains, and four cats consumed 32-37 PV strain-i...