3 documents found, page 1 of 1
Ginger (Zingiber officinale Roscoe) as a nutraceutical: Focus on the metabolic,...
Pagano, Ester; Souto, Eliana B.; Durazzo, Alessandra; Sharifi-Rad, Javad; Lucarini, Massimo; Souto, Selma E.; Salehi, Bahare; Zam, WissamGinger (from the rizhome of Zingiber officinale Roscoe) has been widely used in ethnomedicine for the cure of several ailments. Main active ingredients include phenolic compounds named gingerols. In modern phytotherapy, ginger preparations are predominantly used to counteract nausea and vomiting in pregnant women. However, a number of other pharmacological actions of potential therapeutic interest, which might ...
Polyphenols: A concise overview on the chemistry, occurrence, and human health
Durazzo, Alessandra; Lucarini, Massimo; Souto, Eliana B.; Cicala, Carla; Caiazzo, Elisabetta; Izzo, Angelo A.; Novellino, Ettore; Santini, AntonelloThis review gives an updated picture of each class of phenolic compounds and their properties. The most common classification implies the subdivision of phenolics in two main groups: flavonoids (e.g., anthocyanins, flavanols, flavanones, flavonols, flavonones, and isoflavones) and non-flavonoids (e.g., phenolic acids, xanthones, stilbens, lignans, and tannins) polyphenols. The great interest in polyphenols is a...
Nanoparticle delivery systems in the treatment of diabetes complications
Souto, Eliana B.; Souto, Selma B.; Campos, Joana R.; Severino, Patricia; Pashirova, Tatiana N.; Zakharova, Lucia Y.; Silva, Amélia M.Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line treatment. This administration route is however associated with limited patients compliance, due to the risk of pain, discomfort and local infection. Nanoparticles have been proposed as insulin carriers to make possible the administra...