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The emergence of pathogenic TNF/iNOS producing dendritic cells (Tip-DCs) in a m...

Bruno Galvão Filho; Júlia Teixeira de Castro; Maria Marta Figueiredo; Claudio Gonçalves Rosmaninho; Lis Ribeiro do Valle Antonelli

Malaria-associated acute respiratory distress syndrome (MA-ARDS) and acute lung injury (ALI) are complications that cause lung damage and often leads to death. The MA-ARDS/ALI is associated with a Type 1 inflammatory response mediated by T lymphocytes and IFN-γ. Here, we used the Plasmodium berghei NK65 (PbN)-induced MA-ALI/ARDS model that resembles human disease and confirmed that lung CD4+ and CD8+ T cells pr...

Date: 2022   |   Origin: Oasisbr

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