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Usefulness of zebrafish larvae to evaluate drug-induced functional and morpholo...

Gorgulho, R.; Jacinto, R.; Lopes, S.S.; SA, Pereira; Tranfield, E.M.; Martins, G.G.; Gualda, E.J.; Derks, R.J.E.; Correia, A.C.; Steenvoorden, E.

Prediction and management of drug-induced renal injury (DIRI) rely on the knowledge of the mechanisms of drug insult and on the availability of appropriate animal models to explore it. Zebrafish (Danio rerio) offers unique advantages for assessing DIRI because the larval pronephric kidney has a high homology with its human counterpart and it is fully mature at 3.5 days post-fertilization. Herein, we aimed to ev...


Insights into the role of Notch signalling in cilia motility regulation

Sampaio, P.; Tavares, B.; Jacinto, R.; Lopes, S.

Supported by FCT-ANR/BEX-BID/0153/2012 grant


Pkd2 affects the architecture of zebrafish left-right organizer

Jacinto, R.; Sampaio, P.; Roxo-Rosa, M.; Lopes, S.

Supported by FCT-ANR/BEX-BID/0153/2012 grant.


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