15 documents found, page 1 of 2
Corrigendum to Analysis of the mechanisms of action of isopentyl caffeate again...
Oliveira, Simone S. C.; Marques, Carine S. F.; Sousa, Damião P. de; Andrade, Luciana N.; Fricks, Alini T.; Jain, Sona; Branquinha, Marta H.Corrigendum to “Analysis of the mechanisms of action of isopentyl caffeate against Leishmania”. Biochimie 189 (2021) 158–167
Bacillus thuringiensis: From biopesticides to anticancer agents
Santos, Edclécia N.; Menezes, Lorenna P.; Dolabella, Silvio S.; Santini, Antonello; Severino, Patrícia; Capasso, Raffaele; Zielinska, AleksandraBacillus thuringiensis (Bt) is a ubiquitous bacterium that produces several proteins that are toxic to different invertebrates such as insects, nematodes, mites, and also some protozoans. Among these, Cry and Cyt proteins are most explored as biopesticides for their action against agricultural pests and vectors of human diseases. In 2000, a group of researchers from Japan isolated parasporal inclusion proteins ...
Are Nanobiosensors an Improved Solution for Diagnosis of Leishmania?
Jain, Sona; Santana, Wanessa; Dolabella, Silvio S.; Santos, André L. S.; Souto, Eliana B.; Severino, PatríciaLeishmaniasis is one of the deadliest neglected tropical diseases affecting 12-15 million people worldwide, especially in middle- and low-income countries. Rapid and accurate diagnosis of the disease is important for its adequate management and treatment. Several techniques are available for the diagnosis of leishmaniasis. Among these, parasitological and immunological tests are most widely used. However, in mo...
Biosurfactants: Properties and Applications in Drug Delivery, Biotechnology and...
Bjerk, Thiago R; Severino, Patricia; Jain, Sona; Marques, Conrado; Silva, Amélia M.; Pashirova, Tatiana; Souto, Eliana B.Surfactants are amphiphilic compounds having hydrophilic and hydrophobic moieties in their structure. They can be of synthetic or of microbial origin, obtained respectively from chemical synthesis or from microorganisms' activity. A new generation of ecofriendly surfactant molecules or biobased surfactants is increasingly growing, attributed to their versatility of applications. Surfactants can be used as drug ...
Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania
Oliveira, Simone S. C.; Marques, Carine S. F.; Sousa, Damião P. de; Andrade, Luciana N.; Fricks, Alini T.; Jain, Sona; Branquinha, Marta H.Leishmaniasis is a neglected parasitic disease for which the conventional treatment can be considered inefficient and extremely aggressive, generating several and severe side effects. Therefore, the discovery of new drug candidates is important for the improvement in the quality of life of patients. Previously, we reported the promising results of isopentyl caffeate (ICaf) against Leishmania chagasi (agent of v...
Overcoming multi-resistant leishmania treatment by nanoencapsulation of potent ...
Oliveira, Simone S. C.; Ferreira, Carine S.; Branquinha, Marta H.; Santos, André L. S.; Chaud, Marco V.; Jain, Sona; Cardoso, Juliana C.Leishmaniasis corresponds to a group of neglected tropical diseases caused by flagellated protozoa belonging to the Leishmania genus. This widely spread illness is found in over 90 countries in the tropic and sub-tropic regions and also in southern Europe. As parasites exclusively infect the highly phagocytic cells (macrophages), this aspect can be exploited for targeted delivery making use of nanoparticles. Dr...
Scientific-technological analysis and biological aspects of entomopathogenic fu...
Aragão, Tarcisio M. S.; Santos, João V. F. C. dos; Santos, Tárcio S.; Souto, Eliana B.; Severino, Patrícia; Jain, Sona; Mendonça, Marcelo da CostaEntomopathogenic fungus belonging to the genus Aschersonia [Sordariomycetes: Hypocreales: Clavicipitaceae] is known for its high virulence against Aleyrodidae and Coccoidea. Its first use as a biological control agent date back to 1921 in Florida, when it was reported to be active against citrus whiteflies. Despite its recognized effectiveness, after a century no formulations based on Aschersonia are available ...
Biosurfactants: properties and applications in drug delivery, biotechnology and...
Bjerk, Thiago R.; Severino, Patricia; Jain, Sona; Marques, Conrado; Silva, Amélia M.; Pashirova, Tatiana; Souto, Eliana B.Surfactants are amphiphilic compounds having hydrophilic and hydrophobic moieties in their structure. They can be of synthetic or of microbial origin, obtained respectively from chemical synthesis or from microorganisms activity. A new generation of ecofriendly surfactant molecules or biobased surfactants is increasingly growing, attributed to their versatility of applications. Surfactants can be used as drug d...
Anti‑leishmanial compounds from microbial metabolites: a promising source
Cunha, Ana F. S. da; Di C. Oliveira, Yvanna L.; Dolabella, Silvio S.; Scher, Ricardo; Souto, Eliana B.; Lopez, Jorge A.; Jain, SonaLeishmania is a complex disease caused by the protozoan parasites and transmitted by female phlebotomine sandfly. The disease affects some of the poorest people on earth with an estimated 700,000 to 1 million new cases annually. The current treatment for leishmaniasis is toxic, long, and limited, in view of the high resistance rate presented by the parasite, necessitating new perspectives for treatment. The dis...
Volatile nitrogenous compounds from bacteria: source of novel bioactive compounds
Valença, Camilla A. S.; Barbosa, Ana A. T.; Souto, Eliana B.; Caramão, Elina B.; Jain, SonaBacteria can produce nitrogenous compounds via both primary and secondary metabolic processes. Many bacterial volatile nitrogenous compounds produced during the secondary metabolism have been identified and reported for their antioxidant, antibacterial, antifungal, algicidal and antitumor activities. The production of these nitrogenous compounds depends on several factors, including the composition of culture m...