10 documents found, page 1 of 1
Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a ...
Braga,Vanessa Nogueira Lages; Juanes,Camila de Carvalho; Peres Júnior,Hélio de Souza; Sousa,José Robson de; Cavalcanti,Bruno CoêlhoAbstract Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week for 2 weeks, animals on control groups received saline, while animals in experimental groups received azoxymethane (15 mg/kg i.p.). The follow up along ...
Effect of red propolis on hamster cheek pouch angiogenesis in a new sponge impl...
Melo,Nayanna de Oliveira Ramos; Juanes,Camila de Carvalho; Alves,Mayara Freire de Alencar; Silva,Emiliano Tiago MeloAbstract Purpose: To evaluate the effects of red propolis on cheek pouch angiogenesis in a hamster new model sponge implant. Methods: Forty eight animals divided into eight groups. (Groups I-IV), the animals were treated for 15 days before and 10 days after sponge implantation. (Groups V-VIII), the animals were treated for 10 days after sponge implantation (GI and GV: red propolis 100 mg/kg, GII and GVI: celeco...
Transitional metaplasia in intestinal epithelium of rats submitted to intestina...
Santos,Alessandra Marques dos; Coelho,Joao Paulo Ferreira; Juanes,Camila de Carvalho; Azevedo,Rafael Barbosa de; Diniz,Clara AraujoAbstract Purpose: To evaluated the effects of L-lysine on the intestinal and urothelial epithelia in cystoplasty in rats. Methods: Twenty-eight 9-week-old rats were assigned to 4 groups: Group A (n=8) cystoplasty followed by administration of L-lysine (150 mg/kg body weight by gavage) for 30 weeks; Group B (n=8) cystoplasty + water for 30 weeks; Group C (n=6) L-lysine for 30 weeks; Group D (n=6) water for 30 we...
Carcinogenesis in rats subjected to a new model ureterosigmoidostomy and treate...
Santos,Alessandra Marques dos; Coelho,Joao Paulo Ferreira; Juanes,Camila de Carvalho; Azevedo,Rafael Barbosa de; Melo,Nayanna de Oliveira RamosABSTRACT PURPOSE: To evaluate the effects of L-lysine on the intestinal and urothelial epithelium of rats subjected to ureterosigmoidostomy (new model for surgical carcinogenesis). METHODS: Forty-two rats, 9 weeks of age, were divided into 6 groups. Animals in groups A, B, C were subjected to ureterosigmoidostomy (US) and treated with L-lysine, celecoxib and H2O, respectively. Groups D, E and F (non-operated co...
Bladder carcinogenesis in rats subjected to ureterosigmoidostomy and treated wi...
Dornelas,Conceição Aparecida; Santos,Alessandra Marques dos; Correia,Antonio Lucas Oliveira; Juanes,Camila de Carvalho; Coelho,João Paulo FerreiraABSTRACT Objective: to evaluate the effect of L-lysine in the bladder and intestinal epithelia in rats submitted to vesicosigmoidostomy. Methods: we divided forty Wistar rats into four groups: group I - control group (Sham); group II - submitted to vesicosigmoidostomy and treated with L-lysine 150mg/kg; group III - submitted only to vesicosigmoidostomy; and group IV - received L-lysine 150mg/kg. After eight wee...
Oil mixes omega 9, 6 and 3, enriched with seaweed, promoted reduction of therma...
Campelo,Ana Paula Bomfim Soares; Campelo,Márcio Wilker Soares; Brito,Gerly Anne de Castro; Jamacaru,Francisco Vagnaldo FechinePURPOSE: To examine the effects of the oil mixes (ω-9, ω-6 and ω-3) in rats subjected to thermal burn. It was also aimed to assess whether the sources of ω3 would interfere with the effect of such mixes on the thermal injury.METHODS:Thirty-six rats distributed into five groups: burned + water, burned + isolipid mix, burned + oil mix 1 (ALA), burned + oil mix 2 (ALA + EPA + DHA of fish) and burned + oil mix 3 (A...
Potential chemoprotective effects of green propolis, L-lysine and celecoxib on ...
Dornelas,Conceição Aparecida; Cavalcanti,Bruno Coelho; Magalhães,Hemerson Iury Ferreira; Jamacaru,Francisco Vagnaldo FechinePURPOSE:To evaluate the genotoxicity of propolis and L-lysine, as well as their effects on the possible cellular damage in erythroblasts (bone marrow) and leukocytes (peripheral blood) caused by the carcinogen BBN (n - butyl - n {4 - hydroxybutyl} nitrosamine) in rats subjected to bladder carcinogenesis and treated with green propolis and L-lysine.METHODS: One hundred and twenty five rats were distributed into ...
Repercussão hepática da carcinogênese colorretal induzida pelo azoximetano
Burlamaqui,Idália Maria Brasil; Dornelas,Conceição Aparecida; Almeida,Paulo Roberto Carvalho; Jamacaru,Francisco Vagnaldo FechineOBJETIVO: Avaliar as repercussões hepáticas da carcinogênese colônica induzida por diferentes doses e tempos de exposição ao azoximetano em ratos Wistar. MÉTODOS: Quarenta e quatro ratos foram distribuídos em quatro grupos. Os animais tinham oito semanas no início do experimento. No grupo 1, receberam 1.0mL de solução salina intraperitonealmente uma vez por semana por duas semanas. No grupo 2, receberam 15 mg/k...
Experimental model of ultrasound thermotherapy in rats inoculated with Walker-2...
Morano,José Antonio Carlos Otaviano David; Cordeiro,Naylana; Guimarães,Sergio Botelho; Jamacaru,Francisco Vagnaldo FechinePURPOSE: To develop a model to evaluate the effects of focal pulsed ultrasound (US) waves as a source of heat for treatment of murine subcutaneous implanted Walker tumor. METHODS: An experimental, controlled, comparative study was conducted. Twenty male Wistar rats (160-300 g) randomized in 2 equal groups (G-1: Control and G-2: Hyperthermia) were inoculated with Walker-256 carcinosarcoma tumor. After 5 days G-2...
L-alanyl-glutamine pretreatment attenuates acute inflammatory response in child...
Cunha Filho,José Ferreira da; Gonçalves,Isabelle Ivo; Guimarães,Sergio Botelho; Jamacaru,Francisco Vagnaldo Fechine; Garcia,José Huygens ParentePURPOSE: To evaluate the effects of L-alanyl-glutamine (L-Ala-Gln) pretreatment on oxidative stress, glycemic control and inflammatory response in children submitted to palatoplasty. METHODS: Thirty male children scheduled for routine palatoplasty, age range 2-10 years, were randomly assigned to 2 groups (n=15): Group A (saline, control) and Group B (L-Ala-Gln). Group A received normal saline 100 ml, delivered ...