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Da procura por liberdade à desilusão : o caso de Cavalos Soltos

Janeiro, André

Este estudo, enquanto proposta de trabalho para a conclusão do mestrado em Estudos Cinematográficos, apoia-se numa reflexão sobre o guião de Cavalos Soltos. Explora-se a estrutura formal de um guião e como esta afeta o desenvolvimento da narrativa, a construção das suas personagens, além de uma breve contextualização histórica de Portugal no século XIX, com um foco na situação política do país, e um estudo dos ...


Phylogeography of hepatitis B virus: the role of Portugal in the early dissemin...

Marcelino, Rute; Ezeonwumelu, Ifeanyi Jude; Janeiro, André; Mimoso, Paula; Matos, Sónia; Briz, Veronica; Pimentel, Victor; Pingarilho, Marta

In Portugal, the genetic diversity, origin of HBV and the Portuguese role in the dissemination of HBV worldwide were never investigated. In this work, we studied the epidemic history and transmission dynamics of HBV genotypes that are endemic in Portugal. HBV pol gene was sequenced from 130 patients followed in Lisbon. HBV genotype A was the most prevalent (n = 54, 41.5%), followed by D (n = 44, 33.8%), and E (...


Phylogeography of hepatitis B virus : the role of Portugal in the early dissemi...

Marcelino, Rute; Ezeonwumelu, Ifeanyi Jude; Janeiro, André; Mimoso, Paula; Matos, Sónia; Briz, Veronica; Pimentel, Victor; Pingarilho, Marta

In Portugal, the genetic diversity, origin of HBV and the Portuguese role in the dissemination of HBV worldwide were never investigated. In this work, we studied the epidemic history and transmission dynamics of HBV genotypes that are endemic in Portugal. HBV pol gene was sequenced from 130 patients followed in Lisbon. HBV genotype A was the most prevalent (n = 54, 41.5%), followed by D (n = 44, 33.8%), and E (...


Detection and quantification of EGFR T790M mutation in liquid biopsies by dropl...

Silveira, Catarina; Sousa, Ana Carla; Janeiro, André; Malveiro, Sara; Teixeira, Encarnação; Brysch, Eva; Pantarotto, Marcos; Felizardo, Margarida

Background: Liquid biopsy allows the identification of targetable cancer mutations in a minimally invasive manner. In patients with advanced non-small cell lung cancer (NSCLC), droplet digital PCR (ddPCR) is increasingly used to genotype the epidermal growth factor receptor (EGFR) gene in circulating cell-free DNA (cfDNA). However, the sensitivity of this method is still under debate. The aim of this study was ...


Characterisation of respiratory disease during the 2010/2011 influenza winter s...

Pechirra, Pedro; Gonçalves, Paulo; Conde, Patrícia; Guiomar, Raquel; Duque, Vítor; Vaz, João; Ribeiro, Graça; Cabral, Rita; Mota Vieira, Luísa


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