2 documents found, page 1 of 1
European contribution to the study of ROS: A summary of the findings and prospe...
Egea, Javier; Fabregat, Isabel; Frapart, Yves M; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; Knaus, Ulla G.The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregu...
Transcription factor NRF2 controls the fate of neural stem cells in the subgran...
Robledinos-Antón, Natalia; Rojo, Ana I; Ferreiro, Elisabete; Núñez, Ángel; Krause, Karl-Heinz; Jaquet, Vincent; Cuadrado, AntonioNeural stem/progenitor cells (NSPCs) located at the subgranular zone (SGZ) of the hippocampus participate in the maintenance of synaptic networks that ensure cognitive functions during life. Although it is known that this neurogenic niche losses activity with oxidative stress and ageing, the molecular events involved in its regulation are largely unknown. Here, we studied the role of transcription factor Nuclea...