2 documents found, page 1 of 1
Shortened derivatives from native antimicrobial peptide LyeTx I: in vitro and i...
Leonardo Lima Fuscaldi; Joaquim Teixeira de Avelar Júnior; Daniel Moreira dos Santos; Daiane Boff; Vívian Louise Soares de OliveiraCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico; FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais; CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; In the continuing search for novel antibiotics, antimicrobial peptides are promising molecules, due to different mechanisms of action compared to classic antibiotics and to their selectivity for interaction w...
Synthesis and antimicrobial evaluation of two peptide LyeTx I derivatives modif...
Leonardo Lima Fuscaldi; Daniel Moreira Dos Santos; Natália Gabriela Silva Pinheiro; Raquel Silva Araújo; André Luís Branco de BarrosBackground: Current diagnostic methods and imaging techniques are not able to differentiate septic and aseptic inflammation. Thus, reliable methods are sought to provide this distinction and scintigraphic imaging is an interesting option, since it is based on physiological changes. In this context, radiolabeled antimicrobial peptides have been investigated as they accumulate in infectious sites instead of asept...