9 documents found, page 1 of 1
Can continuous glucose monitoring predict cystic fibrosis-related diabetes and ...
Zorron,Mariana; Marson,Fernando Augusto Lima; Morcillo,André Moreno; Gonçalves,Aline Cristina; El Beck,Mayra de Souza; Ribeiro,José DirceuABSTRACT Objective: To determine whether abnormal continuous glucose monitoring (CGM) readings (hypoglycemia/hyperglycemia) can predict the onset of cystic fibrosis-related diabetes (CFRD) and/or clinical impairment (decline in BMI and/or FEV1) in pediatric patients with cystic fibrosis (CF). Methods: This was a longitudinal prospective cohort study involving CF patients without diabetes at baseline. The mean f...
Volumetric capnography versus spirometry for the evaluation of pulmonary functi...
Almeida-Junior,Armando; Marson,Fernando Augusto Lima; Almeida,Celize Cruz Bresciani; Ribeiro,Maria Ângela Gonçalves Oliveira; Paschoal,Ilma AparecidaAbstract Objective: To compare the values of the markers for volumetric capnography and spirometry and their ability to classify children and adolescents with asthma, cystic fibrosis (CF), and healthy controls. Methods: This was a cross-sectional study that included 103 patients with controlled persistent allergic asthma, 53 with CF and a healthy control group with 40 volunteers (aged 6 to 15 years), of both se...
Influence of AIDS antiretroviral therapy on the growth pattern,
Golucci,Ana Paula Brigatto Simões; Marson,Fernando Augusto Lima; Valente,Mariana Freitas Fedato; Branco,Maira Migliari; Prado,Camila CarboneAbstract Objectives: Human immunodeficiency virus infection can result in the early impairment of anthropometric indicators in children and adolescents. However, combined antiretroviral therapy has improved, in addition to the immune response and viral infection, the weight and height development in infected individuals. Therefore, the objective was to evaluate the effect of combined antiretroviral on the growt...
Chloride and sodium ion concentrations in saliva and sweat as a method to diagn...
Gonçalves,Aline Cristina; Marson,Fernando Augusto Lima; Mendonça,Regina Maria Holanda; Bertuzzo,Carmen Sílvia; Paschoal,Ilma AparecidaAbstract Objective: Cystic fibrosis diagnosis is dependent on the chloride ion concentration in the sweat test (≥ 60 mEq/mL - recognized as the gold standard indicator for cystic fibrosis diagnosis). Moreover, the salivary glands express the CFTR protein in the same manner as sweat glands. Given this context, the objective was to verify the correlation of saliva chloride concentration and sweat chloride concent...
Variants in the interleukin 8 gene and the response to inhaled bronchodilators ...
Furlan,Larissa Lazzarini; Ribeiro,José Dirceu; Bertuzzo,Carmen Sílvia; Salomão Junior,João Batista; Souza,Dorotéia Rossi SilvaAbstract Objective: Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306, and rs2227307) and their association with the response to inhaled bronchodilators in cystic fibrosis patients...
Sweat test and cystic fibrosis: overview of test performance at public and priv...
Servidoni,Maria Fátima; Gomez,Carla Cristina Souza; Marson,Fernando Augusto Lima; Toro,Adyléia Aparecida Dalbo ContreraABSTRACT Objective: The sweat test (ST) measures chloride levels in sweat and is considered the gold standard for the diagnosis of cystic fibrosis (CF). However, the reliability of a ST depends on their being performed by experienced technicians and in accordance with strict guidelines. Our aim was to evaluate how sweat stimulation, sweat collection, and chloride measurement are performed at 14 centers (9 publi...
Effect of exercise test on pulmonary function of obese adolescents,
Faria,Alethéa Guimarães; Ribeiro,Maria Angela G.O.; Marson,Fernando Augusto Lima; Schivinski,Camila Isabel S.; Severino,Silvana DalgeOBJECTIVE:to investigate the pulmonary response to exercise of non-morbidly obese adolescents, considering the gender.METHODS:a prospective cross-sectional study was conducted with 92 adolescents (47 obese and 45 eutrophic), divided in four groups according to obesity and gender. Anthropometric parameters, pulmonary function (spirometry and oxygen saturation [SatO2]), heart rate (HR), blood pressure (BP), respi...
Effect of exercise test on pulmonary function of obese adolescents,
Faria,Alethéa Guimarães; Ribeiro,Maria Angela G.O.; Marson,Fernando Augusto Lima; Schivinski,Camila Isabel S.; Severino,Silvana DalgeOBJECTIVE:to investigate the pulmonary response to exercise of non-morbidly obese adolescents, considering the gender.METHODS:a prospective cross-sectional study was conducted with 92 adolescents (47 obese and 45 eutrophic), divided in four groups according to obesity and gender. Anthropometric parameters, pulmonary function (spirometry and oxygen saturation [SatO2]), heart rate (HR), blood pressure (BP), respi...
Mutações do gene cystic fibrosis transmembrane conductance regulator e deleções...
Lima,Carmen Silvia Passos; Ortega,Manoela Marques; Marson,Fernando Augusto Lima; Zulli,Roberto; Ribeiro,Antônio Fernando; Bertuzzo,Carmen SilviaOBJETIVO: Determinar os efeitos que a mutação do gene cystic fibrosis transmembrane conductance regulator (CFTR) e da deleção dos genes glutationa S-transferase (GST) mu-1 (GSTM1) e teta-1 (GSTT1) têm na evolução clínica da fibrose cística (FC) em pacientes da região sudeste do Brasil. MÉTODOS: Entre março de 2002 e março de 2005, incluímos no estudo todos os pacientes com FC atendidos consecutivamente no Depar...