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Ensuring safety in cytotoxic drug preparation: A systematic review of guideline...

Moreira, Fernando; Jesus, Ângelo; Pinho, Cláudia; Santos, Marlene; Serdoura, Mélanie; Cruz, Agostinho; Moreira, Fernando; Jesus, Ângelo; Pinho, Cláudia

Chemotherapy preparation involves the use of specific techniques and equipment, given the need to maintain preparation sterility and its strict prescribed composition, and avoid occupational exposure to cytotoxic agents. This study aims to identify the most relevant contents for pharmacy professionals' education and training programs and to elucidate the evaluation procedure these professionals should follow wh...


Exploring the role of oral antidiabetic medications as adjuncts in depression t...

Santos, Marlene; Santos, Angela; Jesus, Ângelo; Jesus, Ângelo

Depression is a complex and multifaceted disorder with a poorly defined etiology and numerous risk factors. Despite the availability of several antidepressant classes, many treatments have limitations that compromise their effectiveness and impact patients’ quality of life.


Safeguarding patients, relatives, and nurses: A screening approach for detectin...

Cardoso, Andreia; Jesus, Ângelo; Barreiros, Luísa; Carvalho, Daniel; Sá, Maria dos Anjos; Carvalho, Susana; Correia, Patrícia; Moreira, Fernando

The leakage of 5-fluorouracil (5-FU) from elastomeric infusion pumps used in cancer therapy poses a potential risk of unintentional exposure to multiple individuals, including patients’ relatives and healthcare professionals, and may also compromise the accurate administration of 5-FU dosages to patients. This study aimed to develop, validate, and apply an analytical method to detect and quantify 5-FU residues ...


Factors influencing the prescription of first-line treatment for type 2 diabete...

Moreira, Helena Silva; Moreira, Fernando; Jesus, Ângelo; Soares, Matilde Monteiro; Santos, Paulo; Moreira, Fernando

Understanding prescribing patterns for type 2 diabetes mellitus, a complex condition affecting over 10% of the global adult population, can optimise prescribing practices, guide policymakers in promoting evidence-based medicine, and help tailor first-line treatments to individual characteristics or specific subgroups, improving patient outcomes. This study aimed to identify factors influencing the prescription ...


Fatores que influenciam a prescrição inicial na diabetes mellitus tipo 2: uma r...

Moreira, Helena; Moreira, Fernando; Jesus, Ângelo; Soares, M. Monteiro; Santos, P.; Moreira, Fernando; Jesus, Ângelo

Compreender os fatores que influenciam os profissionais de saúde nas suas preferências de prescrição na diabetes tipo 2, uma condição heterogénea e complexa, é fundamental para aprimorar a prática clínica. Este conhecimento também contribui para a personalização dos tratamentos de primeira linha, ajustando-os às características individuais ou a subgrupos específicos, com o objetivo de melhorar os resultados em ...


Exploring alternative potentialities of portuguese and spanish craft beers: ant...

Pereira, Maria João; Santos, Diana; Cruz, Agostinho; Jesus, Ângelo; Martins, João P.; Moreira, Fernando; Santos, Marlene; Pinho, Cláudia

Craft beer has gained popularity due to its unique sensory characteristics and complex matrix with nutritional and potential health benefits. Studies linking beer consumption to skin conditions are limited, however, the high content of bioactive compounds is related to biological activities such as antibacterial, anti-inflammatory, anti-oxidative, and anti-carcinogenic. This study aims to evaluate the antioxida...


Knowledge of vulvovaginal candidiasis characteristics, signs, symptoms, and app...

Oliveira, Tiago; Jesus, Ângelo; Martins, João P.; Correia, Patrícia; Moreira, Fernando; Moreira, Fernando; Oliveira Martins, João Paulo

Vulvovaginal candidiasis (VVC) is a common cause of vaginitis. Over-the-counter drugs are usually dispensed by pharmacy professionals to treat this condition without prior medical consultation. This study aimed at assessing the knowledge of Portuguese pharmacy professionals regarding VVC. An online questionnaire including questions about the symptoms and treatment of VVC was distributed between March and April ...


Pharmacovigilance of radiopharmaceuticals: Challenges and opportunities

Martins, Sara; Jesus, Ângelo; Martín-Suárez, Ana

Radiopharmaceuticals are unique in that they contain radioactive isotopes which emit radiation for diagnostic or therapeutic purposes.1 They are also used in very small dosages when compared to conventional drugs and the frequency of administrating radiopharmaceuticals in an individual during is lifetime is also very low. Nevertheless due to their specific nature, radiopharmaceuticals require careful monitoring...


Beer with probiotics: Benefits and challenges of their incorporation

Santos, Diana; Barreiros, Luisa; Jesus, Ângelo; Silva, Ana Luísa; Martins, João Paulo; Oliveira, Ana Isabel; Pinho, Cláudia; Jesus, Ângelo

Beer is considered one of the most consumed beverages worldwide and a potential vehicle for probiotics. However, there are several technical challenges to overcome during the production and storage of beers, as probiotics must remain viable until the moment of consumption. Therefore, this work aims to discuss how the incorporation of probiotics improves or adds value to beer and which variables influence the vi...


Segurança e eficácia do uso de inibidores da PARP no tratamento do cancro do ov...

Jesus, Ângelo; Pinto, Rafaela; Jesus, Ângelo

O cancro da mama é um dos cancros mais comuns na mulher. O cancro do ovário, embora tenha uma taxa de incidência relativamente baixa, quando é detetado está geralmente numa fase muito avançada, o que resulta num mau prognóstico e, consequentemente, numa elevada taxa de mortalidade. Estes cancros têm uma forte componente genética de onde resulta uma perda da proteína funcional através da linha germinal ou mutaçã...


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