OBJECTIVE: To perform a molecular characterization of the C1q, C2 and C4 genes in patients with juvenile systemic lupus erythematosus. METHODS: Patient 1 (P1) had undetectable C1q, patient 2 (P2) and patient 3 (P3) had decreased C2 and patient 4 (P4) had decreased C4 levels. All exons and non-coding regions of the C1q and C2 genes were sequenced. Mononuclear cells were cultured and stimulated with interferon ga...
OBJECTIVE: The aim of this study was to assess the IgE serum levels in juvenile systemic lupus erythematosus patients and to evaluate possible associations with clinical and laboratory features, disease activity and tissue damage. METHODS: The IgE serum concentrations in 69 consecutive juvenile systemic lupus erythematosus patients were determined by nephelometry. IgG, IgM and IgA concentrations were measured b...
P. 562-589,Sept./Oct.; Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-10-07T16:33:12Z No. of bitstreams: 1 27764.pdf: 525852 bytes, checksum: 9b214ededd47e9832b185d3b0678236c (MD5); Made available in DSpace on 2011-10-07T16:33:12Z (GMT). No. of bitstreams: 1 27764.pdf: 525852 bytes, checksum: 9b214ededd47e9832b185d3b0678236c (MD5) Previous issue date: 2009; Crianças e adolescentes com doenças...