2 documents found, page 1 of 1
Preserving cognitive function in patients with Alzheimer's disease: The Alzheim...
Liu, Jie; Van Beusekom, Heleen; Bu, Xian‐Le; Chen, Gong; Rosado de Castro, Paulo Henrique; Chen, Xiaochun; Chen, Xiaowei; Clarkson, Andrew N.The global trend toward aging populations has resulted in an increase in the occurrence of Alzheimer's disease (AD) and associated socio-economic burdens. Abnormal metabolism of amyloidâ β (Aβ) has been proposed as a signiï¬ cant pathomechanism in AD, supported by results of recent clinical trials using antiâ Aβ antibodies. Nonetheless, the cognitive beneï¬ ts of the current treatments are limited. The etiol...
Basilar artery occlusion management: specialist perspectives from an internatio...
Edwards, Christopher; Drumm, Brian; Siegler, James E.; Schonewille, Wouter J.; Klein, Piers; Huo, Xiaochuan; Chen, Yimin; Abdalkader, MohamadBackground and purpose: Two early basilar artery occlusion (BAO) randomized controlled trials did not establish the superiority of endovascular thrombectomy (EVT) over medical management. While many providers continue to recommend EVT for acute BAO, perceptions of equipoise in randomizing patients with BAO to EVT versus medical management may differ between clinician specialties. Methods: We conducted an intern...