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The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Diffe...

Flegel, J; Shaaban, S; Jia, ZJ; Schulte, B; Lian, Y; Krzyzanowski, A; Metz, M; Schneidewind, T; Wesseler, F; Flegel, A; Reich, A; Brause, A; Xue, G

Identification and analysis of small molecule bioactivity in target-agnostic cellular assays and monitoring changes in phenotype followed by identification of the biological target are a powerful approach for the identification of novel bioactive chemical matter in particular when the monitored phenotype is disease-related and physiologically relevant. Profiling methods that enable the unbiased analysis of comp...


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