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pH sensitive mesoporous nanohybrids with charge-reversal properties for antican...

Wu, Bozhen; Deng, Shunshu; Zhang, Shihao; Jiang, Jia; Han, Baosan; Li, Yulin

The surface/interface state of nanomaterials plays a key role on their biomedical applications. Nanotechnology offers a versatile means to develop nanoparticles with well-defined architecture. In this study, mesoporous silica nanoparticles were firstly loaded with an anticancer drug (doxorubicin, DOX), which were then decorated with a cationic oligomer (low molecular weight polyethyleneimine, LPEI) to acquire a...


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