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Patch testing with 2.0% (0.60 mg/cm2) formaldehyde instead of 1.0% (0.30 mg/cm2...

Pontén, A; Aalto-Korte, K; Agner, T; Andersen, KE; Gimenez-Arnau, AM; Gonçalo, Margarida; Goossens, A; Johansen, JD; Le Coz, CJ; Maibach, HI

BACKGROUND: The currently used patch test concentration for formaldehyde is 1.0% (wt/vol) in water. However, clinical experience and previous studies suggest that 1.0% might be insufficient for detecting an optimized number of clinically relevant cases of contact allergy to formaldehyde. OBJECTIVES: To validate earlier patch test results for comparison of 1% (wt/vol) and 2% (wt/vol) formaldehyde in water, and t...


Follow-up of the monitored levels of preservative sensitivity in Europe. Overvi...

Svedman, C; Andersen, KE; Brandão, FM; Bruynzeel, DP; Diepgen, TL; Frosch, PJ; Rustemeyer, T; Gimnez-Arnau, A; Gonçalo, Margarida; Goossens, A


p-Phenylenediamine sensitization is more prevalent in central and southern Euro...

Thyssen, JP; Andersen, KE; Bruze, M; Diepgen, T; Giménez-Arnau, AM; Gonçalo, Margarida; Goossens, A; Le Coz, C; McFadden, J; Rustemeyer, T; White, IR

BACKGROUND: Positive patch test reactions to p-phenylenediamine (PPD) are common. PPD is used in oxidative hair dyes and is also present in dark henna temporary 'tattoos'. Cross-sensitization to other contact allergens may occur. Because subjects sensitized to PPD are at risk of clinically severe reactions upon hair dyeing, there is a need for 'current' prevalence data on PPD sensitization. OBJECTIVES: To compa...


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