Made available in DSpace on 2022-04-28T21:24:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-01-01; The effect was investigated of the K+ channel blocker, glibenclamide, on the ability of Crotalus durissus cumanensis venom (CDCM) to promote peripheral antinociception. This was measured by formalin-induced nociception in male Swiss mice. CDCM (200 and 300 μg/kg) produced an antinociceptive effect durin...
Trypanosoma cruzi, the etiologic agent of Chagas disease, remains a p ublic health problem in the Americas. In the present study, we evaluated th e effects of L-amino acid oxidase from Bothrops marajoensis venom (BmLAAO) on the all evolutive forms of T. cruzi . Epimastigote forms of T. cruzi , were cultived in LIT medium, at 28ºC in BmLAAO pr esence for 48 and 72h. Trypomastigote were obtained from the supernat...
Ophidian accidents involving species of the genus Crotalus, are usually serious and frequently fatal due to the frequency of acute renal failure. Unfortunately, there have been few studies of the toxinologic effects of Crotalus durissus cumanensis venom. The renal effects of the venom used in this study were observed by perfusion of isolated kidneys. Infusion of C. d. cumanensis venom (10 µg/mL) produced an inc...