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Assessing the impact of TiO2 nanomaterials on intestinal cells

Rolo, Dora; Pereira, Joana F.S.; Gonçalves, Lídia; Bettencourt, Ana; Jordan, Peter; Silva, Maria João; Matos, Paulo; Louro, Henriqueta

Understanding the potential impact of nanomaterials (NMs) on human health requires further investigation into the organ-specific nano-bio interplay at the cellular and molecular levels. We showed increased chromosomal damage in intestinal cells exposed to some of in vitro digested Titanium dioxide (TiO2) NMs. The present study aimed to explore possible mechanisms linked to the uptake, epithelial barrier integri...


Retraction notice to “WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate ...

Henriques, Andreia F.A.; Matos, Paulo; AS, Carvalho; Azkargorta, Mikel; Elortza, Felix; Matthiesen, Rune; Jordan, Peter

Publisher Copyright: © 2025 Elsevier Inc.; This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editors-in-Chief. After concerns about figure accuracy in figure 3 of the article were raised, the authors checked their submitted figure and shared the original images with the edito...


Adverse Outcome Pathways Associated with the Ingestion of Titanium Dioxide Nano...

Rolo, Dora; Assunção, Ricardo; Ventura, Célia; Alvito, Paula; Gonçalves, Lídia; Martins, Carla; Bettencourt, Ana; Jordan, Peter; Vital, Nádia

Funding Information: This research was funded by the Portuguese Foundation for Science and Technology FCT/MCTES through national funds (PIDDAC), PTDC/SAU-PUB/29481/2017 and co-funded by UIDB/00009/2020 (Centre for Toxicogenomics and Human Health—ToxOmics (UIDP/00009/2020; UIDB/00009/2020), iMed.ULisboa (UIDB/04138/2020+UIDP/04138/2020), CESAM (UIDP/50017/2020+UIDB/50017/2020+LA/P/0094/2020), and BioISI (UID/MUL...


WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expressio...

Henriques, Andreia F.A.; Matos, Paulo; AS, Carvalho; Azkargorta, Mikel; Elortza, Felix; Matthiesen, Rune; Jordan, Peter

This work was supported by Fundação para a Ciência e Tecnologia (FCT) [grants PTDC/SAU-MET/117236/2010 to PJ, grant UID/MULTI/ 04046/2019 to the research unit BioISI, and fellowship SFRH/BD/ 106080/2015 from the BioSYS PhD programme PD65-2012 to AFAH]. The authors acknowledge José Ferrão for regular mycoplasma testing in cultured cells and Patrícia Barros for critical reading of the manuscript. Anthony Albiston...


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