5 documents found, page 1 of 1
Internal Medicine at the Hospital Center of Baixo Vouga
Jorge, Rosa
Weber-Christian disease: unknown etiology systemic panniculitis.
Oliveira, Anabela; Rodrigues, Sandra; Jorge, Rosa; Crespo, JorgePanniculitis is an inflammation occurring within adipose tissue. This process is often associated with auto-immune diseases, infections, malignancy and others diseases of unknown cause. We report a 16-year-old woman with constitutional symptoms and relapsing nonsuppurative nodular panniculitis. The etiological study didn't identify any associated disease, on admission or in 2,5 years of follow-up. This is a cas...
Drug-induced hepatitis treated with corticosteroids – a clinical case report
Oliveira, Anabela; Rodrigues, Sandra; Jesus, Gorete; Jorge, RosaThe authors report the case of a 46 year-old female, with no relevant pathological background, who was prescribed cefuroxime axetil and nimesulide, and fi fteen days later, developed general malaise, asthenia, jaundice and coluria.On being hospitalized, the patient showed an increase of transaminases (ALT= 1747 UI/l) and hyperbilirubinaemia (total bil. = 4.6 mg/dl). As the condition evolved, the jaundice became...
Germline MUTYH (MYH) mutations in portuguese individuals with multiple colorect...
Isidro, Glória; Laranjeira, Francisco; Pires, Ana; Leite, Júlio; Regateiro, Fernando; Sousa, F. Castro; Soares, José; Castro, Clara; Giria, JoãoGerminal mutations in the base excision repair (BER) gene MUTYH (MYH) have recently been described in association with predisposition to multiple colorectal adenomas and cancer. In contrast to the classic dominant condition of familial adenomatous polyposis (FAP) due to germinal mutations in the APC gene, the MYH polyposis is an autosomal recessive disease. The identification of individuals affected by MYH poly...