ABSTRACT Introduction: Dysproteinemia is associated with kidney damage and treatment of underlying conditions is crucial to minimize kidney damage. The aim of this study was to describe and analyze the characteristics and outcome of the patients diagnosed with dysproteinemia-associated kidney disease with initial renal presentation. Methods: We performed a retrospective observational study of the patients admit...
ABSTRACT Urinary tract infection is an important cause of hospitalization, morbidity and mortality, being responsible for an important fraction of health expenses. The main risk factors are urine flow obstruction, urinary catheters, immunosuppression and diabetes mellitus. We present a case of pyelonephritis that culminated in nephrectomy, finally unravelling an unexpected diagnosis. A 52-year-old male presente...
Abstract Introduction: The use of Rituximab (RTX) in glomerular diseases (GD) has increased in the past years, although it is still only used in a small fraction of patients. Methods: A single center retrospective study of adult patients with membranous nephropathy (MN), focal segmental glomerulosclerosis (FSGS), lupus nephritis (LN), and vasculitis treated with RTX as first or second-line therapy was conducted...
Vascular access (VA) dysfunction is an important cause of morbidity and mortality in the hemodialysis (HD) population. Regardless of the increasing prevalence of HD patients with complex VA, the definitions of VA failure (VAF) or end-stage VA failure (ES-VAF) are still being discussed and there is no current guideline that provides recommendation for solving the problem of complicated vascular access. The aim o...
Abstract Introduction: Intra-atrial catheter (IAC) placement through an open surgical approach has emerged as a life-saving technique in hemodialysis (HD) patients with vascular access exhaustion. Objective: To assess the complications of IAC placement, as well as patient and vascular access survival after this procedure. Methods: The authors retrospectively analyzed all seven patients with vascular capital exh...
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in Caucasian adults aged over 60 years old. Approximately two thirds of cases of membranous nephropathy (MN) in adults are primary (idiopathic), and the remaining are secondary forms which have been attributed to a variety of agents or conditions. Recent advances in pathophysiology and the availability of new laboratory diagnostic method...
Chronic kidney disease (CKD) is associated to significant infection incidence and severity, the cause of death of, approximately, 20% of end-stage renal disease patients. Close to 80% of all infections in these patients can be related to organ or tissue other than vascular access, reflecting immune system dysfunction related to several mechanisms. Strongyloides stercoralis is an endemic nematode found especiall...
The increasing prevalence of end-stage chronic kidney disease associated with advances in treatment is expected to lead to improved survival rates of chronic haemodialysis patients in Portugal. Establishing and maintaining vascular access patency is becoming a challenging issue in these patients. We present a case report of a multiple vascular access failure patient to whom a novel vascular access device was im...
Background: Understanding the aetiology and approach to management of chronic kidney disease presenting in the paediatric age range continues to represent a true challenge. With the improvement of paediatric care, the number of patients reaching adulthood has increased in recent decades, and it is well known that the transition period from paediatric to adult care is critical; it is associated with a high rate ...
Vascular access problems are an important cause of compulsory transfer to peritoneal dialysis. Surprisingly, little is known about the effect of these transfers on peritoneal dialysis adequacy, patient or technique survival. We have analysed retrospectively a cohort of 75 patients treated at the Peritoneal Dialysis Unit of Centro Hospitalar Lisboa Norte - Hospital de Santa Maria during the year 2011. Vascular ...