22 documents found, page 1 of 3
The disparity of measuring bone mineral content using bioimpedance and dual-ene...
Crispilho,Shirley Ferraz; Duque,Eduardo Jorge; Bezerra,Kalyanna Soares; Pereira,Rosa Maria R.; Jorgetti,Vanda; Elias,Rosilene M.; Moysés,Rosa M. A.Abstract Introduction: Body composition is critical for the evaluation of patients with Chronic Kidney Disease (CKD) and can be obtained from either multifrequency bioelectrical impedance analysis (BIA) or dual-energy absorptiometry (DXA). Although the discrepancy between the results obtained from both methods has already been described, reasons are unknown, and might be related to secondary hyperparathyroidism...
High prevalence of biochemical disturbances of chronic kidney disease - mineral...
Weissheimer,Rafael; Bucharles,Sergio Gardano Elias; Truyts,Cesar Augusto Madid; Jorgetti,Vanda; Figueiredo,Ana Elizabeth; Barrett,PasqualAbstract Introduction: Chronic kidney disease - mineral and bone disorders (CKD-MBD) are common in dialysis patients. Definition of targets for calcium (Ca), phosphorus (P), parathormone (iPTH), and alkaline phosphatase (ALP) and their treatment recommendations, are provided by international guidelines. There are few studies analyzing CKD-MBD in peritoneal dialysis (PD) patients and the impact of guidelines on ...
Cardiovascular mortality in peritoneal dialysis: the impact of mineral disorders
Truyts,César; Custodio,Melani; Pecoit-Filho,Roberto; Moraes,Thyago Proenca de; Jorgetti,VandaAbstract Introduction: Mineral and bone disorders (MBD) are associated with higher mortality in dialysis patients. The main guidelines related to the subject, Kidney Disease Outcomes Quality Initiative (KDOQI) and Kidney Disease: Improving Global Outcomes (KDIGO), were elaborated based on published information from hemodialysis participants. The aim of our study was to evaluate the impact of calcium (Ca), phosp...
Parathyroid hormone levels after parathyroidectomy for secondary hyperparathyro...
Nascimento Junior,Climério Pereira; Arap,Sergio Samir; Custodio,Melani Ribeiro; Massoni Neto,Ledo Mazzei; Brescia,Marília D’Elboux GuimarãesSUMMARY OBJECTIVE: The parathormone level after parathyroidectomy in dialysis patients are of interest. Low levels may require cryopreserved tissue implantation; however, the resection is necessary in case of recurrence. We analyzed post parathyroidectomy parathormone levels in renal hyperparathyroidism. METHODS: Prospective observation of postoperative parathormone levels over defined periods in a cohort of di...
Digital radiography as an alternative method in the evaluation of bone density ...
Castro,Bárbara Bruna Abreu de; Carmo,Wander Barros; Oliveira,Roberto Sotto Maior Fortes; Peters,Vera Maria; Jorgetti,Vanda; Custodio,Melani RibeiroABSTRACT Introduction: Digital radiography (DRx) may provide a suitable alternative to investigate mineral and bone disorder (MBD) and loss of bone density (BD) in rodent models of chronic kidney disease (CKD). The objective of this study was to use DRx to evaluate BD in CKD rats, and to evaluate the correlation between DRx findings and serum MBD markers and bone histomorphometry. Methods: Uremia was induced by...
Chronic kidney disease is a main confounding factor for 25-vitamin D measurement
Machado,Hanna Karla Andrade Guapyassú; Martins,Carolina Steller Wagner; Jorgetti,Vanda; Elias,Rosilene Motta; Moysés,Rosa Maria AffonsoAbstract Background: Current guidelines recommend assessment of 25-vitamin D status in patients with chronic kidney disease (CKD). Although significant differences among assays have been described, the impact of CKD on this variability has never been tested. Methods: We tested the variability between two 25-vitamin D assays in patients with CKD (eGFR < 60 mL/min/1.73m2) who had consecutive 25-vitamin D measurem...
Renal osteodystrophy and clinical outcomes: data from the Brazilian Registry of...
Carbonara,Cinthia Esbrile Moraes; Reis,Luciene Machado dos; Quadros,Kélcia Rosana da Silva; Roza,Noemi Angelica Vieira; Sano,RafaelABSTRACT Introduction: Mineral and bone disorders (MBD) are major complications of chronic kidney disease (CKD)-related adverse outcomes. The Brazilian Registry of Bone Biopsy (REBRABO) is an electronic database that includes renal osteodystrophy (RO) data. We aimed to describe the epidemiological profile of RO in a sample of CKD-MBD Brazilian patients and understand its relationship with outcomes. Methods: Bet...
The enigma of aluminum deposition in bone tissue from a patient with chronic ki...
Meira,Rodrigo Dias de; Carbonara,Cinthia Esbrile Moraes; Quadros,Kélcia Rosana da Silva; Santos,Carolina Urbini dos; Schincariol,PatríciaABSTRACT About four decades ago, the relationship between dialysis-dementia and aluminum (Al) began to be established. The restriction of drugs containing Al and improvements on water quality used for dialysis resulted in the clinical disappearance of Al intoxication. However, high prevalence of Al deposition in bone tissue from Brazilian dialysis patients is still being detected. Through the case report of a p...
Early postoperative parathormone sampling and prognosis after total parathyroid...
Nascimento Júnior,Climério Pereira do; Brescia,Marília D'Elboux Guimarães; Custódio,Melani Ribeiro; Massoni Neto,Ledo Mazzei; Silveira,André AlbuquerqueAbstract Introduction: There is possibility of a supernumerary hyperplastic parathyroid gland in dialysis patients after total parathyroidectomy and autograft in dialysis patients. Objective: To test if the early postoperative measure of parathyroid hormone (PTH) can identify persistent hyperparathyroidism. Methods: A prospective cohort of dialysis patients submitted to parathyroidectomy had PTH measured up to ...
Histomorphometric analysis of the femoral neck in patients with and without fem...
Souza,Caio Gonçalves de; Jorgetti,Vanda; Reis,Luciene Machado dos; Croci,Alberto TesconiOBJECTIVE: To determine, through bone histomorphometry in femoral neck, whether there are differences in the cancellous bone of the proximal femur from female patients over 60 years old who had femoral neck fracture and similar patients who did not have such fracture.METHODS: We analyzed the trabecular part of the femur of 13 female patients, aged over 60 years old, by the bone histomorphometry method. Seven of...