7 documents found, page 1 of 1
Correction: Jose et al. Transferrin-Conjugated Docetaxel–PLGA Nanoparticles for...
Jose, Sajan; Cinu, Thomas A.; Sebastian, Rosmy; Shoja, M. H.; Aleykutty, N. A.; Durazzo, Alessandra; Lucarini, Massimo; Santini, AntonelloIn the original publication [...]
Correction: Jose et al. Transferrin-Conjugated Docetaxel-PLGA Nanoparticles for...
Jose, Sajan; Cinu, Thomas A; Sebastian, Rosmy; Shoja, M H; Aleykutty, N A; Durazzo, Alessandra; Lucarini, Massimo; Santini, Antonello; Souto, E. B.In the original publication [...].
Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome-Strate...
Vieira, Raquel; Souto, Selma B.; Sánchez-López, Elena; Machado, Ana López; Severino, Patrícia; Jose, Sajan; Santini, Antonello; Fortuna, AnaDiabetes is a complex disease characterized by hyperglycemia, together with polyuria, polydipsia, and polyphagia. While Type 1 diabetes mellitus (T1DM) results from genetic, environmental, or immune dysfunction factors leading to pancreatic β-cell destruction depriving the organism from endogenous insulin, Type 2 diabetes mellitus (T2DM) is characterized by peripheral insulin resistance. Depending on the type o...
Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome-Review...
Vieira, Raquel; Souto, Selma B.; Sánchez-López, Elena; Machado, Ana López; Severino, Patrícia; Jose, Sajan; Santini, Antonello; Fortuna, A.Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia together with disturbances in the metabolism of carbohydrates, proteins and fat, which in general results from an insulin availability and need imbalance. In a great number of patients, marketed anti-glycemic agents have shown poor effectiveness in maintaining a long-term glycemic control, thus being associated with severe adv...
Transferrin-conjugated docetaxel-PLGA nanoparticles for tumor targeting: influe...
Jose, Sajan; Cinu, Thomas A.; Sebastian, Rosmy; Shoja, M. H.; Aleykutty, N. A.; Durazzo, Alessandra; Lucarini, Massimo; Santini, AntonelloTargeted drug delivery systems are commonly used to improve the therapeutic index of anti-cancer drugs by increasing their selectivity and reducing systemic distribution and toxicity. Ligand-conjugated nanoparticles (NPs) can be effectively applied for active chemotherapeutic targeting to overexpressed receptors of tumor cells. In this study, transferrin (Tf) was successfully conjugated with poly-l-lactic-co-gl...
Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndrome - revi...
Vieira, Raquel; Souto, Selma B.; Sánchez-López, Elena; Machado, Ana López; Severino, Patricia; Jose, Sajan; Santini, Antonello; Fortuna, AnaDiabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia together with disturbances in the metabolism of carbohydrates, proteins and fat, which in general results from an insulin availability and need imbalance. In a great number of patients, marketed anti-glycemic agents have shown poor effectiveness in maintaining a long-term glycemic control, thus being associated with severe adv...
Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndromestrateg...
Vieira, Raquel; Souto, Selma B.; Sánchez-López, Elena; López Machado, Ana; Severino, Patricia; Jose, Sajan; Santini, Antonello; Silva, Amelia M.Diabetes is a complex disease characterized by hyperglycemia, together with polyuria, polydipsia, and polyphagia. While Type 1 diabetes mellitus (T1DM) results from genetic, environmental, or immune dysfunction factors leading to pancreatic ß-cell destruction depriving the organism from endogenous insulin, Type 2 diabetes mellitus (T2DM) is characterized by peripheral insulin resistance. Depending on the type o...