4 documents found, page 1 of 1
Sensitivity and specificity of the circulating cathodic antigen rapid urine tes...
Fernanda Teixeira Ferreira; Thiago André Fidelis; Thiago Almeida Pereira; Alba Otoni; Leonardo Campos Queiroz; Frederico Figueiredo AmâncioINTRODUCTION: The Kato-Katz technique is the standard diagnostic test for Schistosoma mansoni infection in rural areas. However, the utility of this method is severely limited by the day-to-day variability in host egg excretion in the stool. In high-transmission areas, the point-of-care circulating cathodic antigen (POC-CCA) urine assay has proven to be a reliable test. However, investigations of the reliabilit...
Thrombocytopenia as a marker of liver steatosis in a low-endemic area for schis...
Albaotoni; Carlos Mauricio de Figueiredo Antunes; Fernanda Ferreira Tavares; Débora Heloísa Quadros Araújo; Thiago de Almeida PereiraIntroduction: Thrombocytopenia is commonly found in patients living in highly endemic areas for Schistosoma mansoni. Recently, different degrees of liver steatosis have also been associated with low platelet counts worldwide. We investigated the association of platelet counts with hepatosplenic schistosomiasis and with liver steatosis in an area of low prevalence of schistosomiasis in Brazil. Method: Pains, a c...
Osteopontin is upregulated in human and murine acute schistosomiasis mansoni
Thiago Almeidapereira; Rafal p Witek; William Evan Secor; Fausto Edmundo Lima Pereira; Jose Roberto Lambertucci; Anna Mae Diehl; Wing-kin SynBackground Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucidated. Osteopontin has been implicated in granulomatous reactions and in acute hepatic injury. Our aims were to evaluate if osteopontin plays a role in ac...
Vestibular Evoked Myogenic Potential (VEMP) Triggered by Galvanic Vestibular St...
Júlia Fonseca de Moraiscaporali; Denise Utsch Gonçalves; Ludimila Labanca; Leonardo Dornas de Oliveira; Guilherme Vaz de Melo TrindadeBackground: Schistosomal myeloradiculopathy (SMR), the most severe and disabling ectopic form of Schistosoma mansoni infection, is caused by embolized ova eliciting local inflammation in the spinal cord and nerve roots. The treatment involves the use of praziquantel and long-term corticotherapy. The assessment of therapeutic response relies on neurological examination. Supplementary electrophysiological exams m...