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Chapter: Carcinogenesis.

Jota Baptista, C; Faustino-Rocha, AI; Seixas, F; Oliveira, PA

Cancer is a complex disease with multiple causes. Many intrinsic and extrinsic factors influence the development of cancer. Intrinsic or host factors include age, sex, genetics, immune system, metabolism, and hormones. Extrinsic factors are divided in different groups, as physical (different types of non-ionizing and ionizing radiations); chemical (as some mineral or organic substances); and biological (produce...


. A spontaneous ovarian teratoma in a FVB/n female mouse: case report and liter...

Oliveira, Paula A.; Faustino-Rocha, Ana I; Gil da Costa, RM; Nascimento-Gonçalves, E; Calado, AM; Jota Baptista, C; Gama, A; Seixas, F

Background: Teratomas are rare types of germ cell neoplasms composed of various differentiated or undifferentiated tissues. Case Description: A 25-week-old female control FVB /n mouse in a 4-week toxicity study presented abdominal distension and poor body condition. It was euthanized, and the necropsy examination revealed a large mass connected to the tip of the right uterine horn, occupying the entire abdomina...


The first full study of heavy metal(loid)s in western-European hedgehogs (Erina...

Jota Baptista, C; Seixas, F; Gonzalo-Orden, JM; Patinha, C; Pato, P; Ferreira da Silva, E; Casero, M; Brazio, E; Brandão, R; Costa, D; Mateus, TL

The western-European hedgehog (Erinaceus europaeus) is an insectivore with a wide distribution in Portugal and a potential tool for biomonitoring relevant One Health hazards, including heavy metal(loid)s’ pollution. The aim of this study was to positively contribute to the current knowledge about the metal(loid) pollution in Portugal. Forty-six hedgehogs (from rescue centres; with known provenance) were necrops...


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