7 documents found, page 1 of 1
Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a ...
Braga,Vanessa Nogueira Lages; Juanes,Camila de Carvalho; Peres Júnior,Hélio de Souza; Sousa,José Robson de; Cavalcanti,Bruno CoêlhoAbstract Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week for 2 weeks, animals on control groups received saline, while animals in experimental groups received azoxymethane (15 mg/kg i.p.). The follow up along ...
Red propolis and L-lysine on angiogenesis and tumor growth in a new model of ha...
Juanes,Camila de Carvalho; Souza,Susana Moreira de; Braga,Vanessa Nogueira Lages; Barreto,Francisco Stefânio; Aguiar,Gisele RochaABSTRACT Objective: To evaluate the effect of red propolis and L-lysine on angiogenesis and tumor growth in a new model of hamster cheek pouch inoculated with Walker 256 tumor cells. Methods: The study consisted of two experiments with four groups each (total: 57 hamsters). In the experiment 1, the animals were inoculated with Walker tumor cells, followed by administration of test substances (red propolis 200mg...
Effect of red propolis on hamster cheek pouch angiogenesis in a new sponge impl...
Melo,Nayanna de Oliveira Ramos; Juanes,Camila de Carvalho; Alves,Mayara Freire de Alencar; Silva,Emiliano Tiago MeloAbstract Purpose: To evaluate the effects of red propolis on cheek pouch angiogenesis in a hamster new model sponge implant. Methods: Forty eight animals divided into eight groups. (Groups I-IV), the animals were treated for 15 days before and 10 days after sponge implantation. (Groups V-VIII), the animals were treated for 10 days after sponge implantation (GI and GV: red propolis 100 mg/kg, GII and GVI: celeco...
Transitional metaplasia in intestinal epithelium of rats submitted to intestina...
Santos,Alessandra Marques dos; Coelho,Joao Paulo Ferreira; Juanes,Camila de Carvalho; Azevedo,Rafael Barbosa de; Diniz,Clara AraujoAbstract Purpose: To evaluated the effects of L-lysine on the intestinal and urothelial epithelia in cystoplasty in rats. Methods: Twenty-eight 9-week-old rats were assigned to 4 groups: Group A (n=8) cystoplasty followed by administration of L-lysine (150 mg/kg body weight by gavage) for 30 weeks; Group B (n=8) cystoplasty + water for 30 weeks; Group C (n=6) L-lysine for 30 weeks; Group D (n=6) water for 30 we...
Carcinogenesis in rats subjected to a new model ureterosigmoidostomy and treate...
Santos,Alessandra Marques dos; Coelho,Joao Paulo Ferreira; Juanes,Camila de Carvalho; Azevedo,Rafael Barbosa de; Melo,Nayanna de Oliveira RamosABSTRACT PURPOSE: To evaluate the effects of L-lysine on the intestinal and urothelial epithelium of rats subjected to ureterosigmoidostomy (new model for surgical carcinogenesis). METHODS: Forty-two rats, 9 weeks of age, were divided into 6 groups. Animals in groups A, B, C were subjected to ureterosigmoidostomy (US) and treated with L-lysine, celecoxib and H2O, respectively. Groups D, E and F (non-operated co...
Bladder carcinogenesis in rats subjected to ureterosigmoidostomy and treated wi...
Dornelas,Conceição Aparecida; Santos,Alessandra Marques dos; Correia,Antonio Lucas Oliveira; Juanes,Camila de Carvalho; Coelho,João Paulo FerreiraABSTRACT Objective: to evaluate the effect of L-lysine in the bladder and intestinal epithelia in rats submitted to vesicosigmoidostomy. Methods: we divided forty Wistar rats into four groups: group I - control group (Sham); group II - submitted to vesicosigmoidostomy and treated with L-lysine 150mg/kg; group III - submitted only to vesicosigmoidostomy; and group IV - received L-lysine 150mg/kg. After eight wee...
Potential chemoprotective effects of green propolis, L-lysine and celecoxib on ...
Dornelas,Conceição Aparecida; Cavalcanti,Bruno Coelho; Magalhães,Hemerson Iury Ferreira; Jamacaru,Francisco Vagnaldo FechinePURPOSE:To evaluate the genotoxicity of propolis and L-lysine, as well as their effects on the possible cellular damage in erythroblasts (bone marrow) and leukocytes (peripheral blood) caused by the carcinogen BBN (n - butyl - n {4 - hydroxybutyl} nitrosamine) in rats subjected to bladder carcinogenesis and treated with green propolis and L-lysine.METHODS: One hundred and twenty five rats were distributed into ...