Hyperglycemia is a frequent complication and its prevalence occurs in up to 38% of hospitalized patients. Such condition may be due to previously known diabetes, stress responsive to associated diseases or treatments or it may due to diabetes only diagnosed during hospitalization. The presence of nosocomial hyperglycemia is associated with prolonged hospitalization time, increased demand for human resources and...
Bisphosphonates are considered first-line agents in the treatment of postmenopausal osteo-porosis based on extensive experience of use, safety, and proven efficacy in reducingvertebral, non-vertebral and femur fractures. However, post-marketing reports based onthe treatment of millions of patients/year over lengthy periods of time have revealed theoccurrence of initially unexpected adverse effects, such as oste...
The main factor of virulence in Clostridium difficile is toxin A (TxA), which can induce inflammation and acute tissue injury in the bowels of animals and humans affected by this organism. The high concentration of adenosine generated upon injury produces a number of antiinflammatory effects limited by rapid degradation by adenosine deaminase. The objective of this study was to determine the effect of EHNA (ery...