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Predictors of Functional Outcome After Symptomatic Intracranial Hemorrhage Comp...

Tsivgoulis, Georgios; Palaiodimou, Lina; Stefanou, Maria-Ioanna; Theodorou, Aikaterini; Kõrv, Janika; Paiva Nunes, Ana; Candelaresi, Paolo

Background and purpose: Several risk factors of symptomatic intracerebral hemorrhage (SICH) following intravenous thrombolysis for acute ischaemic stroke have been established. However, potential predictors of good functional outcome post-SICH have been less studied. Methods: Patient data registered in the Safe Implementation of Treatment in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) from 200...


Obesity and the risk of cryptogenic ischemic stroke in young adults

Jaakonmäki, Nina; Zedde, Marialuisa; Sarkanen, Tomi; Martinez-Majander, Nicolas; Tuohinen, Suvi; Sinisalo, Juha; Ryödi, Essi; Autere, Jaana

Objectives: We examined the association between obesity and early-onset cryptogenic ischemic stroke (CIS) and whether fat distribution or sex altered this association. Materials and methods: This prospective, multi-center, case-control study included 345 patients, aged 18-49 years, with first-ever, acute CIS. The control group included 345 age- and sex-matched stroke-free individuals. We measured height, weight...


Global impact of COVID-19 on stroke care and IV thrombolysis

Nogueira, Raul G.; Qureshi, Muhammad M.; Abdalkader, Mohamad; Martins, Sheila Ouriques; Yamagami, Hiroshi; Qiu, Zhongming; Mansour, Ossama Yassin

Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified ...


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